Christophe Moreno
Université libre de Bruxelles
281 Papers
1.9K Citations
Christophe Moreno is an academic researcher from Université libre de Bruxelles. The author has contributed to research in topics: Medicine & Hepatitis C. The author has an hindex of 53, co-authored 259 publications. Previous affiliations of Christophe Moreno include Free University of Brussels & University of Toronto.
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Papers
Alcoholic hepatitis: Towards an era of personalised management.
TL;DR: Diagnosis of alcoholic hepatitis, the different scores to assess severity of the disease, indications for corticosteroid therapy and alternative therapeutic options for non-responders to medical therapy are discussed.
Prednisolone With vs Without Pentoxifylline and Survival of Patients With Severe Alcoholic Hepatitis: A Randomized Clinical Trial
Philippe Mathurin,Alexandre Louvet,Alain Duhamel,Pierre Nahon,Nicolas Carbonell,Jérôme Boursier,Rodolphe Anty,Emmanuel Diaz,Dominique Thabut,Romain Moirand,Didier Lebrec,Christophe Moreno,N. Talbodec,Thierry Paupard,Sylvie Naveau,Christine Silvain,Georges-Philippe Pageaux,Rodolphe Sobesky,V. Canva-Delcambre,Sébastien Dharancy,Julia Salleron,Thong Dao +21 more
TL;DR: In patients with alcoholic hepatitis, 4-week treatment with pentoxifylline and prednisolone, compared with prednisolia alone, did not result in improved 6-month survival, and the study may have been underpowered to detect a significant difference in incidence of hepatorenal syndrome, which was less frequent in the group receiving pentoxifyinglline.
Transoral gastroplasty is safe, feasible, and induces significant weight loss in morbidly obese patients: results of the second human pilot study
Christophe Moreno,Jean Closset,Sonia Dugardeyn,Marie Barea,A. Mehdi,L. Collignon,Marc Zalcman,M. Baurain,O. Le Moine,Jacques Devière +9 more
TL;DR: This second pilot trial confirmed the feasibility and safety of transoral gastroplasty and a dramatic improvement in quality-of-life measures was observed in all patients, which is encouraging in terms of safety, early weight loss, and quality of life.
Improvement of sleep architecture parameters in cirrhotic patients with recurrent hepatic encephalopathy with the use of rifaximin.
Marie Bruyneel,Thomas Sersté,Walter W. Libert,Sandra Van den Broecke,Lieveke Ameye,Bernard Dachy,Jean-Pierre Mulkay,Christophe Moreno,Thierry Gustot +8 more
TL;DR: On 24-h polysomnography (PSG), rifaximin improves objective sleep architecture parameters with no changes in the subjective quality of sleep and sleepiness.
Epigenetic basis for monocyte dysfunction in patients with severe alcoholic hepatitis.
Laura Weichselbaum,Abdulkader Azouz,Kinga K. Smolen,Jishnu Das,Jishnu Das,Marion Splittgerber,Antonia Lepida,Christophe Moreno,Jonas Schreiber,Thomas Sersté,Eric Trepo,Frédérick Libert,Thierry Gustot,Thierry Gustot,Stanislas Goriely +14 more
TL;DR: The altered transcriptional program and functional properties of monocytes from sAH patients contributing to their susceptibility to infection have strong epigenetic determinants.