Christophe Cellier
Paris Descartes University
27 Papers
164 Citations
Christophe Cellier is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Intraepithelial lymphocyte & Coeliac disease. The author has an hindex of 17, co-authored 27 publications. Previous affiliations of Christophe Cellier include University of Paris & French Institute of Health and Medical Research.
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Papers
Refractory sprue, coeliac disease, and enteropathy-associated T-cell lymphoma
Christophe Cellier,Eric Delabesse,Christine Helmer,Natacha Patey,Claude Matuchansky,Bana Jabri,Elizabeth Macintyre,Nadine Cerf-Bensussan,Nicole Brousse +8 more
TL;DR: It is suggested that refractory sprue associated with an aberrant clonal IEL may be the missing link between coeliac disease and T- cell lymphoma and may be classified as cryptic enteropathy-associated T-cell lymphoma.
765
A Direct Role for NKG2D/MICA Interaction in Villous Atrophy during Celiac Disease
Sophie Hue,Jean-Jacques Mention,Renato C. Monteiro,Shao Ling Zhang,Christophe Cellier,Jacques Schmitz,Virginie Verkarre,Nassima Fodil,Seiamak Bahram,Nadine Cerf-Bensussan,Sophie Caillat-Zucman +10 more
TL;DR: It is shown that MICA is strongly expressed at epithelial cell surface in patients with active disease and is induced by gliadin or its p31-49 derived peptide upon in vitro challenge, which supports a key role for MIC/NKG2D in the activation of intraepithelial immunity in response to danger.
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Inhibition of TGF-β Signaling by IL-15: A New Role for IL-15 in the Loss of Immune Homeostasis in Celiac Disease
Mélika Benahmed,Mélika Benahmed,Bertrand Meresse,Bertrand Meresse,Bertrand Arnulf,Bertrand Arnulf,Bertrand Arnulf,Ullah Barbe,Ullah Barbe,Jean-Jacques Mention,Jean-Jacques Mention,Virginie Verkarre,Virginie Verkarre,Virginie Verkarre,Matthieu Allez,Christophe Cellier,Christophe Cellier,Olivier Hermine,Olivier Hermine,Olivier Hermine,Nadine Cerf–Bensussan,Nadine Cerf–Bensussan +21 more
TL;DR: Impairment of TGF-beta-mediated signaling by IL-15 might promote and sustain intestinal inflammation in celiac disease, and this data provide a new rationale for the potent proinflammatory effects ofIL-15, and further support the concept that IL- 15 is a meaningful therapeutic target in inflammatory diseases associated with irreducible elevation of Il-15.
191
Refractory coeliac sprue is a diffuse gastrointestinal disease
Virginie Verkarre,Vahid Asnafi,Thierry Lecomte,N Patey Mariaud-De Serre,M Leborgne,Etienne Grosdidier,C. Le Bihan,E Macintyre,Christophe Cellier,Nadine Cerf-Bensussan,Nicole Brousse +10 more
TL;DR: The immunophenotypically aberrant monoclonal IEL population present in the small intestine of patients with RCS frequently disseminates to the blood and the entire gastrointestinal epithelium, suggesting that this is a diffuse gastrointestinal disease.
172
Enteropathy associated T cell lymphoma in celiac disease: a large retrospective study.
Georgia Malamut,Georgia Malamut,Olivia Chandesris,Olivia Chandesris,Virginie Verkarre,Virginie Verkarre,Virginie Verkarre,Bertrand Meresse,Bertrand Meresse,Céline Callens,Céline Callens,Elizabeth Macintyre,Elizabeth Macintyre,Yoram Bouhnik,Jean-Marc Gornet,Matthieu Allez,Raymond Jian,Anne Berger,Gilles Châtellier,Nicole Brousse,Nicole Brousse,Nicole Brousse,Olivier Hermine,Olivier Hermine,Nadine Cerf-Bensussan,Nadine Cerf-Bensussan,Christophe Cellier,Christophe Cellier +27 more
TL;DR: This study underlines the prognostic value of celiac disease type in patients with T-cell lymphoma, and suggests that a combination of nutritional, chemotherapy and reductive surgery may improve survival.
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