Christine Oley
University of Birmingham
9 Papers
30 Citations
Christine Oley is an academic researcher from University of Birmingham. The author has contributed to research in topics: Basal Cell Nevus Syndrome & Nevoid basal-cell carcinoma syndrome. The author has an hindex of 9, co-authored 9 publications. Previous affiliations of Christine Oley include Royal Brisbane and Women's Hospital & Newcastle University.
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Papers
•Journal Article
Further localization of the gene for nevoid basal cell carcinoma syndrome (NBCCS) in 15 Australasian families: linkage and loss of heterozygosity.
Georgia Chenevix-Trench,Georgia Chenevix-Trench,Carol Wicking,Jenny Berkman,Helen Sharpe,Athel Hockey,Eric Haan,Christine Oley,Christine Oley,David Ravine,Anne M. Turner,David E. Goldgar,Jeffrey Searle,Brandon J. Wainwright +13 more
TL;DR: It is determined that the NBCCS gene is also linked to this region in Australasian pedigrees and that there is no significant evidence of heterogeneity, and the gene is probably a tumor-suppressor gene.
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Crossover analysis in a British family suggests that Coffin-Lowry syndrome maps to a 3.4-cM interval in Xp22.
TL;DR: A recombination in a carrier from a British family mean that DXS365 is the closest proximal flanking marker identified to date for the region thought to contain the CLS gene, which reduces the region of interest by approximately 2.2 cM.
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Fourteen new cases contribute to the characterization of the 7q11.23 microduplication syndrome
Nathalie Van der Aa,Liesbeth Rooms,Geert Vandeweyer,Jenneke van den Ende,Edwin Reyniers,Marco Fichera,Corrado Romano,Barbara Delle Chiaie,Geert Mortier,Björn Menten,Anne Destree,Isabelle Maystadt,Katrin Männik,Ants Kurg,Tiia Reimand,Dom McMullan,Christine Oley,Louise Brueton,Ernie M.H.F. Bongers,Bregje W.M. van Bon,Rolph Pfund,Sébastien Jacquemont,Alessandra Ferrarini,Danielle Martinet,Connie Schrander-Stumpel,Alexander P.A. Stegmann,Suzanna G.M. Frints,Bert B.A. de Vries,Berten Ceulemans,R. Frank Kooy +29 more
TL;DR: This patient collection demonstrates that the 7q11.23 microduplication not only causes language delay, but is also associated with congenital anomalies and a recognizable face.
Clinical and molecular genetic features of Beckwith-Wiedemann syndrome associated with assisted reproductive technologies.
Derek Lim,Sarah Bowdin,Louise Tee,Gail Kirby,Edward Blair,Alan Fryer,Wayne Lam,Christine Oley,Trevor Cole,Louise Brueton,Wolf Reik,Fiona Macdonald,Eamonn R. Maher +12 more
TL;DR: These findings provide further evidence that ART may be associated with disturbed normal genomic imprinting in a subset of children.