Christine McBeth
University of Saint Mary
11 Papers
32 Citations
Christine McBeth is an academic researcher from University of Saint Mary. The author has contributed to research in topics: Biology & T-cell receptor. The author has an hindex of 9, co-authored 11 publications. Previous affiliations of Christine McBeth include Fred Hutchinson Cancer Research Center & Boston University.
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Papers
Crystal structure of a γδ T-cell receptor specific for the human MHC class I homolog MICA
Bin Xu,Juan C. Pizarro,Margaret A. Holmes,Christine McBeth,Veronika Groh,Thomas A. Spies,Roland K. Strong +6 more
TL;DR: Interaction analyses showed that MIC binding by the two receptors was mutually exclusive, and analysis of relative binding kinetics suggested sequential recognition, defining constraints for the temporal organization of γδ T-cell/target cell interfaces.
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3D bioprinting of GelMA scaffolds triggers mineral deposition by primary human osteoblasts.
Christine McBeth,Jasmin Lauer,Michael Ottersbach,Jennifer Campbell,Andre Sharon,Alexis F. Sauer-Budge +5 more
TL;DR: A gelatin methacryloyl (GelMA) scaffold is generated, using an extrusion-based 3D bioprinter, which can be directly printed on and grafted to the titanium implant surface and is able to trigger mineral deposition of both MG63 osteoblasts and primary normal human osteoblast in the absence of any exogenous osteogenic factors.
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Cm-p5: an antifungal hydrophilic peptide derived from the coastal mollusk Cenchritis muricatus (Gastropoda: Littorinidae)
Carlos López-Abarrategui,Christine McBeth,Santi M. Mandal,Zhen-Yu J. Sun,Gregory J. Heffron,Annia Alba-Menéndez,Ludovico Migliolo,Osvaldo Reyes-Acosta,Monica Garcia-Villarino,Diego O. Nolasco,Rosana Falcão,Mariana Dornelles Cherobim,Simoni Campos Dias,Wolfgang Brandt,Ludger A. Wessjohann,Michael N. Starnbach,Octavio L. Franco,Anselmo J. Otero-González +17 more
TL;DR: Cm‐p5 (SRSE‐LIVHQRLF), a peptide derived from the marine mollusk Cenchritis muricatus peptide Cm •p1, has a significantly increased fungistatic activity against pathogenic Candida albicans while exhibiting low toxic effects against a cultured mammalian cell line.
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Low-cost, real-time, continuous flow PCR system for pathogen detection
B. Leticia Fernández-Carballo,Ian McGuiness,Christine McBeth,Maxim Kalashnikov,Salvador Borrós,Andre Sharon,Alexis F. Sauer-Budge +6 more
TL;DR: A portable and low cost point-of-care (POC) PCR system based on continuous flow PCR which maintains fixed temperatures zones and pushes the PCR solution between two heated areas allowing for faster heat transfer and as a result, a faster PCR.
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Microfluidic advances in phenotypic antibiotic susceptibility testing
Jennifer Campbell,Christine McBeth,Maxim Kalashnikov,Anna K. Boardman,Andre Sharon,Alexis F. Sauer-Budge +5 more
TL;DR: This Perspective will cover the advances made in the field of microfluidic, phenotypic antibiotic susceptibility testing (AST) over the past two years, and gives the perspective on the major hurdles still facing the field, including the need for rapid sample preparation and affordable detection technologies.
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