Christine L. Mummery
Leiden University Medical Center
451 Papers
4.3K Citations
Christine L. Mummery is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Embryonic stem cell & Stem cell. The author has an hindex of 94, co-authored 416 publications. Previous affiliations of Christine L. Mummery include Loyola University Medical Center & University Medical Center Utrecht.
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Papers
Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes Under Defined Conditions.
Cathelijne W. van den Berg,David A. Elliott,Stefan R. Braam,Christine L. Mummery,Richard P. Davis +4 more
TL;DR: A directed differentiation monolayer protocol is developed that can be used to generate cultures comprising ~50% cardiomyocytes, in which both the culture of the undifferentiated human pluripotent stem cells (hPSCs) and the differentiation procedure itself are defined and serum-free.
Toward Human Models of Cardiorenal Syndrome in vitro
Beatrice Gabbin,Viviana Meraviglia,Christine L. Mummery,Ton J. Rabelink,Berend J. van Meer,Cathelijne W. van den Berg,Milena Bellin +6 more
TL;DR: An overview of the existing in vivo and in vitro models to study Cardiorenal syndrome, their limitations and new perspectives on how heart-kidney physiological and pathological interaction could be investigated in vitro for future applications are provided.
Is heart regeneration on the right track
TL;DR: A number of recent studies in rodents showing that cardiac fibroblasts can be reprogrammed, via miRNAs and a transcription factor 'cocktail', to express cardiac genes, which resulted in improved cardiac function in the animals, suggesting a new way forward for fixing damaged heart tissue.
•Book
Stem Cells : Scientific Facts and Fiction
Bernard A.J. Roelen,Anja van de Stolpe,Christine L. Mummery +2 more
- 09 Feb 2021
TL;DR: The main goal of the book is to provide readers with an overview of the scientific facts about stem cells and its promising effects on the human body, as well as on the creation of new drugs and medicines.
An experimental correction for arginine-to-proline conversion artifacts in SILAC-based quantitative proteomics.
Dennis Van Hoof,Martijn W. H. Pinkse,Martijn W. H. Pinkse,Dorien Ward-van Oostwaard,Christine L. Mummery,Albert J. R. Heck,Jeroen Krijgsveld +6 more
TL;DR: An experimental correction for arginine-to-proline conversion artifacts in SILAC-based quantitative proteomics and its implications for proteomics research are investigated.