Christine L. Mummery
Leiden University Medical Center
451 Papers
4.3K Citations
Christine L. Mummery is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Embryonic stem cell & Stem cell. The author has an hindex of 94, co-authored 416 publications. Previous affiliations of Christine L. Mummery include Loyola University Medical Center & University Medical Center Utrecht.
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Papers
Stage-specific appearance of the mouse antigen TEC-3 in normal and nuclear transfer bovine embryos: re-expression after nuclear transfer.
Annelies E. P. van Stekelenburg-Hamers,Heggert Rebel,Wouter G. van Inzen,Frans A. M. de Loos,Maarten Drost,Christine L. Mummery,Sjerp M. Weima,Sjerp M. Weima,Alan O Trounson,Alan O Trounson +9 more
TL;DR: The data suggest that the bovine embryonic nucleus may be able to revert to the equivalent of an earlier developmental stage when transferred to ooplasm, and is then capable of following the normal developmental program.
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Unlocking Personalized Biomedicine and Drug Discovery with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Fit for Purpose or Forever Elusive?
Tessa de Korte,Puspita A Katili,Nurul A N Mohd Yusof,Berend J. van Meer,Umber Saleem,Francis L. Burton,Godfrey L. Smith,Peter Clements,Christine L. Mummery,Thomas Eschenhagen,Arne Hansen,Chris Denning +11 more
TL;DR: Whether technologies using human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) could complement existing assays to improve discovery and safety while reducing socioeconomic costs and assisting with regulatory guidelines on cardiac safety assessments is considered.
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Patent
Methods of Inducing Differentiation of Stem Cells
Christine L. Mummery
- 23 Jul 2002
TL;DR: In this article, a method for inducing differentiation of embryonic stem cells into muscle cells or vascular endothelial cells was proposed, which was later used for therapeutic purposes, such as using the differentiated cells of the present method.
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Knock-in of integrin β1D affects primary but not secondary myogenesis in mice
Ana Sofia Cachaço,Susana M. Chuva de Sousa Lopes,Ingrid Kuikman,Fernanda Bajanca,Kuniya Abe,Christian Baudoin,Christian Baudoin,Arnoud Sonnenberg,Christine L. Mummery,Sólveig Thorsteinsdóttir +9 more
TL;DR: These results demonstrate for the first time distinct roles for β 1 integrins in primary versus secondary myogenesis and that the β 1A and β1D variants are not functionally equivalent in this process.
Identification and characterization of polypeptide growth factors secreted by murine embryonal carcinoma cells
Everardus J.J. van Zoelen,Theodora M. J. Ward‐Van Oostwaard,Rienk Nieuwland,Bart van der Burg,Adriana J.M. van den Eijnden-van Raaij,Christine L. Mummery,Siegfried W. de Laat +6 more
TL;DR: This is the first demonstration for secretion of transforming growth factor-alpha by an equivalent of early embryonic cells, and the differences in growth factor production by various embryonal carcinoma cells are discussed in relation to the developmental origin of these cell lines.
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