Christine Coméra
University of Toulouse
4 Papers
Christine Coméra is an academic researcher from University of Toulouse. The author has contributed to research in topics: Intestinal absorption & Chylomicron. The author has an hindex of 4, co-authored 4 publications. Previous affiliations of Christine Coméra include French Institute of Health and Medical Research.
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Papers
Food-grade TiO 2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon.
Sarah Bettini,Elisa Boutet-Robinet,Christel Cartier,Christine Coméra,Eric Gaultier,J. Dupuy,Nathalie Naud,Sylviane Taché,Patrick Grysan,Solenn Reguer,Nathalie Thieriet,Matthieu Réfrégiers,Dominique Thiaudière,Jean Pierre Cravedi,Marie Carrière,Jean-Nicolas Audinot,Fabrice Pierre,Laurence Guzylack-Piriou,Eric Houdeau +18 more
TL;DR: In rats orally exposed for one week to E171 at human relevant levels, titanium was detected in the immune cells of Peyer’s patches (PP) as observed with the TiO2-NP model NM-105, and these data should be considered for risk assessments of the susceptibility to Th17-driven autoimmune diseases and to colorectal cancer in humans exposed toTiO2 from dietary sources.
Basal Ti level in the human placenta and meconium and evidence of a materno-foetal transfer of food-grade TiO2 nanoparticles in an ex vivo placental perfusion model.
A Guillard,Eric Gaultier,Christel Cartier,Laurent Devoille,Johanna Noireaux,L Chevalier,Mathieu Morin,Flore C. Grandin,Marlène Z. Lacroix,Christine Coméra,A Cazanave,A de Place,Véronique Gayrard,Véronique Bach,Karen Chardon,N Bekhti,K Adel-Patient,Christophe Vayssière,Christophe Vayssière,Paola Fisicaro,N Feltin,F de la Farge,Nicole Picard-Hagen,Bruno Lamas,Eric Houdeau +24 more
TL;DR: Results show a materno-foetal transfer of TiO 2 particles during pregnancy, with food-gradeTiO 2 as a potential source for foetal exposure to NPs, and emphasize the need for risk assessment of chronic exposure to TiO2 -NPs during pregnancy.
Exposure to dietary lipid leads to rapid production of cytosolic lipid droplets near the brush border membrane
Zeina Soayfane,François Tercé,Michela Cantiello,Horst Robenek,Michel Nauze,Valérie Bézirard,Sophie Allart,Bruno Payré,Florence Capilla,Christel Cartier,Christine Peres,Talal Al Saati,Vassilia Theodorou,David W. Nelson,Chi-Liang Eric Yen,Xavier Collet,Christine Coméra,Christine Coméra +17 more
TL;DR: These findings suggest that following their uptake by enterocytes, lipids can be partially metabolized at the BBM and packaged into CLD for their transportation to the ER.
Jejunal villus absorption and paracellular tight junction permeability are major routes for early intestinal uptake of food-grade TiO 2 particles: an in vivo and ex vivo study in mice
Christine Coméra,Christel Cartier,Eric Gaultier,Olivier Catrice,Quentin Panouille,Sarah El Hamdi,Kristof Tirez,Inge Nelissen,Vassilia Theodorou,Eric Houdeau +9 more
TL;DR: After a single E171 dose in mice, early intestinal uptake of TiO2 particles mainly occurred through the villi of the small intestine, which, in contrast to the PP, represent the main absorption surface in thesmall intestine.