Christian Gosch
Vienna University of Technology
25 Papers
96 Citations
Christian Gosch is an academic researcher from Vienna University of Technology. The author has contributed to research in topics: Chalcone synthase & Malus. The author has an hindex of 14, co-authored 25 publications. Previous affiliations of Christian Gosch include University of Vienna.
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Papers
Phloridzin: biosynthesis, distribution and physiological relevance in plants.
TL;DR: The phenolic compound phloridzin is a prominent member of the chemical class of dihydrochalcones, which are phenylpropanoids and the effect on human health - especially diabetes - and membrane permeability is well documented.
260
Cloning and heterologous expression of glycosyltransferases from Malus x domestica and Pyrus communis, which convert phloretin to phloretin 2'-O-glucoside (phloridzin)
TL;DR: It is shown that different glycosyltransferases from M. x domestica could be responsible for phloridzin formation in planta and that Pyrus communis has the ability to glycoslyate phloretin, although no phlorein derivatives are present in this genus.
72
Investigation of the biosynthesis of 3-deoxyanthocyanins in Sinningia cardinalis
Christopher S. Winefield,David H. Lewis,Ewald E. Swinny,Huaibi Zhang,H. Steve Arathoon,Thilo C. Fischer,Heidrun Halbwirth,Karl Stich,Christian Gosch,Gert Forkmann,Kevin M. Davies +10 more
TL;DR: A mechanism of 3-deoxyflavonoid biosynthesis in sinningia similar to that reported for Zea mays is suggested, in which lack of F3H activity allows action of the DFR/FNR on flavanone substrates and production of flavan-4-ols.
47
Dihydroflavonol 4-Reductase Genes Encode Enzymes with Contrasting Substrate Specificity and Show Divergent Gene Expression Profiles in Fragaria Species
Silvija Miosic,Jana Thill,Malvina Milosevic,Christian Gosch,Sabrina Pober,Christian Molitor,Shaghef Ejaz,Annette Rompel,Karl Stich,Heidi Halbwirth +9 more
TL;DR: During fruit ripening, strawberries show distinct changes in the flavonoid classes that accumulate, switching from the formation of flavan 3-ols and flavonols in unripe fruits to the accumulation of anthocyanins in the ripe fruits.
Isolation of dihydroflavonol 4-reductase cDNA clones from Angelonia x angustifolia and heterologous expression as GST fusion protein in Escherichia coli.
Christian Gosch,Karthik Mudigere Nagesh,Jana Thill,Silvija Miosic,Sylvia Plaschil,Malvina Milosevic,Klaus Olbricht,Shaghef Ejaz,Annette Rompel,Karl Stich,Heidi Halbwirth +10 more
TL;DR: Both the GST fusion protein and purified DFR minus the GST tag could be stored at −80°C for several months without loss of enzyme activity and demonstrated identical substrate specificity as the recombinant enzyme obtained from heterologous expression in yeast.