Christian G. Hartinger
University of Auckland
265 Papers
2.3K Citations
Christian G. Hartinger is an academic researcher from University of Auckland. The author has contributed to research in topics: Chemistry & Ruthenium. The author has an hindex of 67, co-authored 248 publications. Previous affiliations of Christian G. Hartinger include University of Vienna & École Polytechnique Fédérale de Lausanne.
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Papers
Gel electrophoresis in combination with laser ablation–inductively coupled plasma mass spectrometry to quantify the interaction of cisplatin with human serum albumin
TL;DR: A method based on SDS‐PAGE separation and laser ablation–inductively coupled plasma‐mass spectrometry (LA–ICP‐MS) for platinum detection in the reaction between human serum albumin (HSA) and cisplatin is presented.
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Cobalt complexes as internal standards for capillary zone electrophoresis–mass spectrometry studies in biological inorganic chemistry
TL;DR: In general, employing Co complexes resulted in improved data sets, particularly with regard to the migration times and peak areas, which resulted, for example, in higher linear ranges for the quantification of cisplatin.
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Tracing the anticancer compound [RuII(η6-p-cymene)(8-oxyquinolinato)Cl] in a biological environment by mass spectrometric methods
TL;DR: The fate of 1 in cells is investigated as well as an analysis method for 1 and its derivatives based on molecular mass spectrometry is developed, which found the compound was still detectable by LC-ESI-TOF-MS after 24 h in cell lysate as its [1 - Cl]+ ion.
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Opening the Lid on Piano‐Stool Complexes: An Account of Ruthenium(II)—Arene Complexes with Medicinal Applications
TL;DR: In this article, the authors describe the origins of the field and highlight developments in the field, including the design of compounds that inhibit enzymes, the application of multinuclear systems to act as drug delivery vehicles, and the development of bioanalytical and biophysical methods to help elucidate the mechanisms by which these compounds function.
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Hyphenation of capillary electrophoresis to inductively coupled plasma mass spectrometry with a modified coaxial sheath-flow interface.
TL;DR: In a set of proof-of-principle experiments employing the anticancer agent cisplatin it was demonstrated that the signal to noise response and sensitivity were considerably improved leading to detection limits for 195Pt of 0.08 μM.
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