Christian Betzel
University of Hamburg
349 Papers
2.8K Citations
Christian Betzel is an academic researcher from University of Hamburg. The author has contributed to research in topics: Protein crystallization & Chemistry. The author has an hindex of 44, co-authored 330 publications. Previous affiliations of Christian Betzel include Eppendorf (Germany) & University of Tübingen.
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Papers
Crystal Structure of Mistletoe Lectin I (ML-I) from Viscum album in Complex with 4-N-Furfurylcytosine at 2.85 Å Resolution
Malik Shoaib Ahmad,Saima Rasheed,Sven Falke,Binish Khaliq,Markus Perbandt,Muhammad Iqbal Choudhary,Wojciech T. Markiewicz,Jan Barciszewski,Christian Betzel +8 more
TL;DR: In this article, the crystal structure of ML from Viscum album in complex with the nucleic acid oxidation product 4-N-furfurylcytosine (FC) refined to 2.85 A resolution.
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Structural investigation of the thymidine phosphorylase from Salmonella typhimurium in the unliganded state and its complexes with thymidine and uridine.
V.V. Balaev,A. A. Lashkov,Azat Gabdulkhakov,Maria V. Dontsova,Tatiana A. Seregina,Alexander Mironov,Christian Betzel,Al'bert M. Mikhailov +7 more
TL;DR: The various structural features of the enzyme which might be responsible for the specificity for thymidine and not for uridine were identified and the presence of the 2'-hydroxyl group in uridine results in a different position of the uridine furanose moiety compared with that of Thymidine, which may be the key element of the substrate specificity.
Crystallization and preliminary X-ray diffraction data of an LNA 7-mer duplex derived from a ricin aptamer.
Charlotte Förster,Dominik Oberthuer,Jiang Gao,André Eichert,Frederick G. Quast,Christian Betzel,Andreas Nitsche,Volker A. Erdmann,Jens P. Fürste +8 more
TL;DR: The terminal helix has been constructed as an ;all-locked' LNA and was successfully crystallized in order to investigate its structural properties and for future stabilization of the aptamer, which showed high affinity in ricin binding.
Human tRNAGly acceptor‐stem microhelix: crystallization and preliminary X‐ray diffraction analysis at 1.2 Å resolution
Charlotte Förster,Karol Szkaradkiewicz,Markus Perbandt,Arnd B. E. Brauer,Tordis Borowski,Jens P. Fürste,Christian Betzel,Volker A. Erdmann +7 more
TL;DR: The human tRNA(Gly) acceptor-stem microhelix was crystallized in an attempt to analyze the structural features that govern the correct recognition of tRNAs by the eukaryotic/archaebacterial-type glycyl-tRNA synthetase.