Christa Schott
Centre national de la recherche scientifique
38 Papers
785 Citations
Christa Schott is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Nitric oxide & Endothelium. The author has an hindex of 24, co-authored 38 publications. Previous affiliations of Christa Schott include University of Strasbourg.
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Papers
Red wine polyphenols prevent angiotensin II-induced hypertension and endothelial dysfunction in rats: Role of NADPH oxidase
Mamadou Sarr,Marta Chataigneau,Sandrine Martins,Christa Schott,Jasser El Bedoui,Min-Ho Oak,Bernard Muller,Thierry Chataigneau,Valérie B. Schini-Kerth +8 more
TL;DR: In this article, the authors examined whether red wine polyphenols prevent the angiotensin II (Ang II)-induced hypertension and endothelial dysfunction in rats, and, if so, to elucidate the underlying mechanism.
Induction of nitric oxide synthase and dual effects of nitric oxide and cyclooxygenase products in regulation of arterial contraction in human septic shock.
Jean-Claude Stoclet,M. C. Martínez,Patrick Ohlmann,Sylvette Chasserot,Christa Schott,Andrei L. Kleschyov,Francis Schneider,Ramaroson Andriantsitohaina +7 more
TL;DR: Results provide direct evidence for the induction of NO synthase in small arteries from patients with septic shock and suggest that in these arteries, increased production of NO, in conjunction with vasodilatory cyclooxygenase metabolites, contributes to counteract hyperreactivity to agonists and decreases the cyclo Oxygenase product-mediated pronounced fading of contraction caused by a high concentration of NE.
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•Journal Article
Nitric oxide and endotoxemia
Jean Claude Stoclet,Ingrid Fleming,Gillian A. Gray,Géraldine Julou-Schaeffer,Francis Schneider,Cathy Schott,Christa Schott,James R. Parratt +7 more
TL;DR: Although LPS can directly act on vascular smooth muscle cells to induce NO-synthase, endothelial cells (and probably other cells) accelerate the induction of vascular NO production and hyporeactivity to norepinephrine.
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Increase in serum NG-hydroxy-l-arginine in rats treated with bacterial lipopolysaccharide
TL;DR: Aortic rings isolated from rats 4 h after an injection i.p. of 30 mg/kg Escherichia coli lipopolysaccharide showed a marked hyporeactivity to noradrenaline, paralleled by an increase in the level of nitrite/nitrate in the serum of lipopoly Saccharide-treated rats, indicative of an enhanced nitric oxide (NO) synthase activity.
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Effect of bacterial lipopolysaccharide on function of rat small femoral arteries.
Francis Schneider,B. Bucher,Christa Schott,A. Andre,Géraldine Julou-Schaeffer,Jean-Claude Stoclet +5 more
TL;DR: Results indicate that LPS treatment induced a NO synthase activity in smooth muscle cells of rat small femoral arteries and that the resulting relaxation was dependent on extracellular L-arginine in these resistance vessels.
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