Chris S. King
UCLA Medical Center
5 Papers
5 Citations
Chris S. King is an academic researcher from UCLA Medical Center. The author has contributed to research in topics: Autoimmune disease & Thyroid. The author has an hindex of 5, co-authored 5 publications. Previous affiliations of Chris S. King include University of California, Los Angeles.
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Papers
Unique attributes of orbital fibroblasts and global alterations in IGF-1 receptor signaling could explain thyroid-associated ophthalmopathy.
Terry J. Smith,Chieh Chih Tsai,Mei Ju Shih,Shanli Tsui,Beiling Chen,Rui Han,Vibha Naik,Chris S. King,Chris Press,Shweta Kamat,Robert A. Goldberg,Richard P. Phipps,Raymond S. Douglas,Andrew G. Gianoukakis +13 more
TL;DR: The laboratory group has focused over the last several years on defining the peculiarities of the human orbital fibroblasts as a strategy for shedding more light on the pathologies occurring in TAO, reasoned that unique properties of these cells might ultimately prove the basis for why the manifestations of Graves' disease occur in an anatomically selective manner.
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IgG from patients with Graves' disease induces IL-16 and RANTES expression in cultured human thyrocytes: A putative mechanism for T cell infiltration of the thyroid in autoimmune disease.
Andrew G. Gianoukakis,Raymond S. Douglas,Chris S. King,William W. Cruikshank,Terry J. Smith,David Geffen +5 more
- 01 Jan 2006
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Immunoglobulin G from patients with Graves' disease induces interleukin-16 and RANTES expression in cultured human thyrocytes: a putative mechanism for T-cell infiltration of the thyroid in autoimmune disease.
Andrew G. Gianoukakis,Raymond S. Douglas,Raymond S. Douglas,Chris S. King,William W. Cruikshank,Terry J. Smith,Terry J. Smith +6 more
TL;DR: It is suggested that thyrocytes can be activated by GD-IgG and IGF-I to express powerful T-cell chemoattractants and participate directly in lymphocyte recruitment through their expression of IL-16 and RANTES.
Hyaluronan accumulation in thyroid tissue: evidence for contributions from epithelial cells and fibroblasts.
Andrew G. Gianoukakis,Timothy A. Jennings,Chris S. King,Christine E. Sheehan,Neil Hoa,Paraskevi Heldin,Terry J. Smith,Terry J. Smith +7 more
TL;DR: It is reported here that levels of hyaluronan are increased in thyroid tissue from individuals with both Graves' disease and Hashimoto's thyroiditis compared with glands uninvolved with autoimmune disorders, and this findings represent potentially important insights into the pathogenesis of autoimmune thyroid diseases.
Children with early-onset inflammatory bowel disease (IBD): analysis of a pediatric IBD consortium registry.
Melvin B. Heyman,Barbara S. Kirschner,Benjamin D. Gold,George D. Ferry,Robert N. Baldassano,Stanley A. Cohen,Harland S. Winter,Patricia Fain,Chris S. King,Terry J. Smith,Hashem B. El-Serag +10 more
TL;DR: This demographically diverse pediatric IBD cohort revealed age-related variation in the distribution of IBD phenotype, with a high prevalence of isolated colonic disease in young children.