Chris Reading
University of Arkansas for Medical Sciences
5 Papers
174 Citations
Chris Reading is an academic researcher from University of Arkansas for Medical Sciences. The author has contributed to research in topics: Bone marrow & CD34. The author has an hindex of 3, co-authored 5 publications.
Chat about Author
Papers
Purified CD34+ Lin- Thy+ stem cells do not contain clonal myeloma cells.
Yair Gazitt,Chris Reading,Ron Hoffman,Amittha Wickrema,David H. Vesole,Sundar Jagannath,Janet Condino,Brenda Lee,Bart Barlogie,Guido Tricot +9 more
TL;DR: Results show that purification of CD34+ Lin- Thy+ cells depletes myeloma cells to undetectable levels from up to 10% present in unsorted PBSCs, thus offering a tool to investigate whether MM relapse after autotransplantation can be reduced markedly.
162
Preliminary clinical findings on NEUMUNE as a potential treatment for acute radiation syndrome
Dwight R. Stickney,Jessie R. Groothuis,Clarence N. Ahlem,Michael R. Kennedy,Barry S Miller,Nanette Onizuka-Handa,Karen M. Schlangen,Daniel A. Destiche,Chris Reading,Armando Garsd,James M. Frincke +10 more
TL;DR: Parenteral administration of 5-AED in aqueous suspension may be a safe and effective means to stimulate innate immunity and alleviate neutropenia and thrombocytopenia associated with ARS.
23
17α-alkynyl 3α, 17β-androstanediol non-clinical and clinical pharmacology, pharmacokinetics and metabolism.
Clarence N. Ahlem,Michael R. Kennedy,Theodore M. Page,David Bell,Evelyn Delorme,Sonia Villegas,Chris Reading,Steven K. White,Dwight R. Stickney,James M. Frincke +9 more
TL;DR: Safety studies conducted in rats and dogs indicated a substantial margin of safety for clinical use, and no evidence of electrocardiographic or neurological effects, although anorexia, thrombocytopenia, and hypokalemia were identified as potentially dose-limiting toxicities at superpharmacological exposures.
13
A New Parasiticidal Compound in T. solium Cysticercosis
Romel Hernández-Bello,Galileo Escobedo,Julio César Carrero,Claudia Cervantes-Rebolledo,Charles Dowding,James M. Frincke,Chris Reading,Jorge Morales-Montor +7 more
TL;DR: The results leave open the possibility of assessing the potential of this hormonal analogue as a possible antiparasite drug, particularly in cysticercosis and taeniosis, in hamsters.
2
HE2100 (androst-5-ene-3β, 17β-diol), an Adrenal Hormone, Protects Rhesus Macaques from Lethal Total Body Irradiation (TBI)- Induced Severe Neutropenia and Thrombocytopenia.
Dwight R. Stickney,Charles Dowding,Simon Authier,Armando Garsd,Nanette Onizuka-Handa,Chris Reading,James M. Frincke +6 more
TL;DR: HE2100 appears to stimulate multi-lineage recovery, via early bone marrow hematopoietic stem cell progenitors following TBI injury in rhesus macaques, and this compound afforded protection of the unsupported animals from lethal irradiation, decreasing the lethality overall.
1