Chris Galanos
Max Planck Society
176 Papers
4.3K Citations
Chris Galanos is an academic researcher from Max Planck Society. The author has contributed to research in topics: Lipid A & Lipopolysaccharide. The author has an hindex of 63, co-authored 175 publications. Previous affiliations of Chris Galanos include University of Texas Southwestern Medical Center.
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Papers
Diurnal Variations in the Human Host Response to Endotoxin
Thomas Pollmächer,Janet Mullington,Carsten Korth,Wolfgang Schreiber,Dirk M. Hermann,Armin Orth,Chris Galanos,Florian Holsboer +7 more
TL;DR: Diurnal variations in the human susceptibility to endotoxin that may be due to a suppression of the biologic effects of TNF-alpha and IL-6 by endogenous glucocorticoids are demonstrated.
95
Isolation, Purification, and Chemical Analysis of the Lipopolysaccharide Analysis of the Lipopolysaccharide and Lipid A of Acinetobacter calcoaceticus NCTC 10305
Helmut Brade,Chris Galanos +1 more
TL;DR: The lipopolysaccharide of Acinetobacter calcoaceticus NCTC 10305 (London) was obtained by a modified phenol/chloroform/light petroleum method from the bacterial cells and from the culture medium in yields of 1.6% and 2.2% respectively (based on the bacterial dry weight).
94
Gamma interferon mediates Propionibacterium acnes-induced hypersensitivity to lipopolysaccharide in mice.
TL;DR: Evidence is provided that IFN-gamma mediates the sensitization towards LPS induced by P. acnes and abolishes the development of hypersensitivity to the lethal action of LPS.
92
Lipopolysaccharides: Structural Principles and Biologic Activities
O Lüderitz,K Tanamoto,Chris Galanos,G R McKenzie,Helmut Brade,Ulrich Zähringer,Ernst Th. Rietschel,Shoichi Kusumoto,Tetsuo Shiba +8 more
TL;DR: These investigations are aimed at verifying the proposed structure of lipid A and at evaluating structure-activity relationships in lipid A analogues, one of the recently available, chemically synthesized lipid A analogueues.
89
Infection of C57BL/10ScCr and C57BL/10ScNCr mice with Leishmania major reveals a role for Toll-like receptor 4 in the control of parasite replication
Pascale Kropf,N. Freudenberg,Christoph Kalis,Manuel Modolell,Shanti Herath,Chris Galanos,Marina A. Freudenberg,Ines Müller +7 more
TL;DR: It is shown that the lack of TLR4 results in an increased permissiveness for parasite growth during the innate and adaptive phase of the immune response and in delayed healing of the cutaneous lesions.
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