Chongren Tang
University of Washington
19 Papers
53 Citations
Chongren Tang is an academic researcher from University of Washington. The author has contributed to research in topics: Cholesterol & Adipose tissue. The author has an hindex of 15, co-authored 19 publications.
Chat about Author
Papers
Serum amyloid A impairs the antiinflammatory properties of HDL
Chang Yeop Han,Chongren Tang,Myriam E. Guevara,Hao Wei,Tomasz Wietecha,Baohai Shao,Savitha Subramanian,Mohamed Omer,Shari Wang,Kevin D. O’Brien,Santica M. Marcovina,Thomas N. Wight,Tomas Vaisar,Maria C. de Beer,Frederick C. de Beer,William R. A. Osborne,Keith B. Elkon,Alan Chait +17 more
TL;DR: Findings indicate that inflammation results in a loss of the antiinflammatory properties of HDL on adipocytes, which appears to partially result from the SAA component of HDL binding to cell-surface proteoglycans, thereby preventing access of HDL to the plasma membrane.
High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis
Anuradha Vivekanandan-Giri,Jessica L. Slocum,Jaeman Byun,Chongren Tang,Robin L. Sands,Brenda W. Gillespie,Jay W. Heinecke,Rajiv Saran,Mariana J. Kaplan,Subramaniam Pennathur +9 more
TL;DR: An increase in MPO-mediated HDL oxidation that is regiospecific in RA and accentuated in those with CVD is reported and raises the possibility that oxidant resistant forms of HDL may attenuate this increased risk of atherosclerosis.
Both STAT3 activation and cholesterol efflux contribute to the anti-inflammatory effect of apoA-I/ABCA1 interaction in macrophages
TL;DR: Mechanistic studies showed that the anti-inflammatory effect of the apoA-I/ABCA1/STAT3 pathway is suppressor of cytokine signaling 3 dependent, and it is suggested that the interaction of apo-I / ABCA1 activates cholesterol efflux and STAT3 branch pathways to synergistically suppress inflammation in macrophages.
55
Acyl-CoA synthetase 1 is required for oleate and linoleate mediated inhibition of cholesterol efflux through ATP-binding cassette transporter A1 in macrophages.
TL;DR: The reduced ABCA1 and cholesterol efflux in macrophages subjected to conditions of diabetes and elevated fatty load may, at least in part, be mediated by ACSL1, a key enzyme mediating acyl-CoA synthesis in Macrophages.
47
Modulation of adipose tissue lipolysis and body weight by high-density lipoproteins in mice.
Hao Wei,Michelle M. Averill,Timothy S. McMillen,F Dastvan,Poulami Mitra,Savitha Subramanian,Chongren Tang,Alan Chait,Renee C. LeBoeuf +8 more
TL;DR: In this paper, male C57BL/6 wild-type (WT), apoA-I deficient (apoAI-I−/−) and apolipoprotein (apo) transgenic mice were fed obesogenic diets (ODs) and monitored for several clinical parameters.