Chong Wang
Peking University
10 Papers
2 Citations
Chong Wang is an academic researcher from Peking University. The author has contributed to research in topics: Biology & Cancer. The author has an hindex of 4, co-authored 8 publications.
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Papers
Aberrant high expression of immunoglobulin G in epithelial stem/progenitor-like cells contributes to tumor initiation and metastasis.
Qinyuan Liao,Wei Liu,Yang Liu,Fulin Wang,Chong Wang,Jingxuan Zhang,Ming Chu,Dongyang Jiang,Lin Xiao,Wenwei Shao,Zhengzuo Sheng,Xia Tao,Lei Huo,Cheng Cameron Yin,Youhui Zhang,Gregory Lee,Jing Huang,Zihai Li,Xiaoyan Qiu +18 more
TL;DR: It is concluded that high expression of IgG is a novel biomarker of tumor progression, metastasis and cancer stem cell maintenance and the potential therapeutic benefits of RP215-recognized IgG targeted strategy are demonstrated.
IgG and IgA with Potential Microbial-Binding Activity Are Expressed by Normal Human Skin Epidermal Cells
Dongyang Jiang,Jing Ge,Qinyuan Liao,Junfan Ma,Yang Liu,Jing Huang,Chong Wang,Weiyan Xu,Jie Zheng,Wenwei Shao,Gregory Lee,Xiaoyan Qiu +11 more
TL;DR: It is speculated that normal human epidermal cells spontaneously express functional immunoglobulin G and IgA, previously thought to be only produced by B cells, and these Igs participate in skin innate immunity.
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Binding of the monoclonal antibody RP215 to immunoglobulin G in metastatic lung adenocarcinomas is correlated with poor prognosis.
Yang Liu,Dan Liu,Chong Wang,Qinyuan Liao,Jing Huang,Dongyang Jiang,Wenwei Shao,Cheng Cameron Yin,Youhui Zhang,Gregory Lee,Xiaoyan Qiu +10 more
TL;DR: The relationship between cancer‐IgG expression in lung adenocarcinoma (ADC) and clinicopathological characteristics and clinical outcome is investigated and cancer cell‐derived immunoglobulin (Ig)G is found to be involved in the pathogenesis and progression of many cancers, including lung cancer.
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IGK with conserved IGKV/IGKJ repertoire is expressed in acute myeloid leukemia and promotes leukemic cell migration
Chong Wang,Miaoran Xia,Miaoran Xia,Xiaoping Sun,Zhiqiao He,Fanlei Hu,Lei Chen,Carlos E. Bueso-Ramos,Xiaoyan Qiu,Xiaoyan Qiu,Cameron C. Yin +10 more
TL;DR: IGK is expressed in myeloblasts and mature myeloid cells from patients with non-hematopoietic neoplasms, and is involved in cell migration, suggesting that myeloids cells-derived IgK may have a role in leukemogenesis and may serve as a novel tumor marker for monitoring minimal residual disease and developing target therapy.
A widely expressed free immunoglobulin κ chain with a unique Vκ4-1/Jκ3 pattern promotes colon cancer invasion and metastasis by activating the integrin β1/FAK pathway.
Qianqian Yang,Dongyang Jiang,Qing Ye,Wenjing Zhou,Junfan Ma,Chong Wang,Zihan Geng,Ming Chu,Jie Zheng,Hongchengcheng Chen,Jing Huang,Hui Dai,Youhui Zhang,Zhanpeng She,Ning Fu,Xiaoyan Qin +15 more
TL;DR: In this paper , a free Igκ light chain with a unique Vκ4-1/Jκ3 rearrangement was found to promote the proliferation, migration and metastasis of colon cancer cells.
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