Chikako Uneyama
57 Papers
800 Citations
Chikako Uneyama is an academic researcher. The author has contributed to research in topics: Offspring & Estrous cycle. The author has an hindex of 24, co-authored 57 publications.
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Papers
Subchronic toxicity study of gallic acid by oral administration in F344 rats.
TL;DR: In this article, the subchronic toxicity of gallic acid (GA) was investigated in F344 rats by feeding diet containing 0, 0.6, 1.7 and 5% GA for 13 weeks.
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Impact of dietary exposure to methoxychlor, genistein, or diisononyl phthalate during the perinatal period on the development of the rat endocrine/reproductive systems in later life.
Naoya Masutomi,Makoto Shibutani,Hironori Takagi,Chikako Uneyama,Noriyuki Takahashi,Masao Hirose +5 more
TL;DR: It is demonstrated that perinatal dietary exposure to EDCs for a limited period causes endocrine disruption in offspring only at high doses.
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Doxorubicin induces male germ cell apoptosis in rats.
Kazutoshi Shinoda,Kunitoshi Mitsumori,Kazuo Yasuhara,Chikako Uneyama,Hiroshi Onodera,Masao Hirose,Masato Uehara +6 more
TL;DR: It is demonstrated that apoptosis plays an important role in the induction of testicular toxicity caused by DXR with meiotically dividing spermatocytes and type A and intermediate sperMatogonia as highly vulnerable target cells.
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Chemopreventive effects of phenethyl isothiocyanate on lung and pancreatic tumorigenesis in N-nitrosobis(2-oxopropyl)amine-treated hamsters.
Akiyoshi Nishikawa,Fumio Furukawa,Chikako Uneyama,Shinichiro Ikezaki,Zen-yo Tanakamaru,Fung-Lung Chung,Michihito Takahashi,Yuzo Hayashi +7 more
TL;DR: PEITC is a remarkably effective chemopreventive agent for the BOP-induced lung and pancreatic tumors in hamsters, and shows a tendency to lower the incidences of liver and renal tumors, although these effects were not statistically significant.
Repeated dose (28 days) oral toxicity study of flutamide in rats, based on the draft protocol for the `Enhanced OECD Test Guideline 407' for screening for endocrine-disrupting chemicals
Kazuhiro Toyoda,Makoto Shibutani,Toru Tamura,Takatoshi Koujitani,Chikako Uneyama,Masao Hirose +5 more
TL;DR: Among the parameters tested in the present experimental system, the weight of endocrine-linked organs and their histopathological assessment, serum hormone levels, and estrous cycle stage allowed the detection of endocrin-related effects of flutamide.
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