Chiara Riva
University of Milano-Bicocca
14 Papers
85 Citations
Chiara Riva is an academic researcher from University of Milano-Bicocca. The author has contributed to research in topics: Chaperone-mediated autophagy & Single-nucleotide polymorphism. The author has an hindex of 10, co-authored 14 publications.
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Papers
NMR-driven identification of anti-amyloidogenic compounds in green and roasted coffee extracts.
Carlotta Ciaramelli,Alessandro Palmioli,Ada De Luigi,Laura Colombo,Gessica Sala,Chiara Riva,Chiara Zoia,Mario Salmona,Cristina Airoldi +8 more
TL;DR: The data showed that green and roasted coffee extracts and their main components, 5-O-caffeoylquinic acid and melanoidins, can hinder Aβ on-pathway aggregation and toxicity in a human neuroblastoma SH-SY5Y cell line.
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Rotenone down-regulates HSPA8/hsc70 chaperone protein in vitro: A new possible toxic mechanism contributing to Parkinson's disease.
Gessica Sala,D Marinig,Chiara Riva,A Arosio,G Stefanoni,Laura Brighina,Matteo Formenti,Lilia Alberghina,Anna Maria Colangelo,Carlo Ferrarese +9 more
TL;DR: It is demonstrated that dysfunction of both CMA and macroautophagy can synergistically exacerbate alpha-synuclein toxicity, suggesting that hsc70 up-regulation may represent a valuable therapeutic strategy for PD.
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Role of sepiapterin reductase gene at the PARK3 locus in Parkinson's disease
Manu Sharma,Demetrius M. Maraganore,John P. A. Ioannidis,John P. A. Ioannidis,Olaf Riess,Jan O. Aasly,Grazia Annesi,Nadine Abahuni,Anna Rita Bentivoglio,Alexis Brice,Christine Van Broeckhoven,Marie-Christine Chartier-Harlin,Alain Destée,Ana Djarmati,Alexis Elbaz,Matthew J. Farrer,Carlo Ferrarese,J. Mark Gibson,Suzana Gispert,Nobutaka Hattori,Barbara Jasinska-Myga,Christine Klein,Suzanne Lesage,Timothy Lynch,Peter Lichtner,Jean-Charles Lambert,Anthony E. Lang,George D. Mellick,George D. Mellick,Francesa de Nigris,Grzegorz Opala,Aldo Quattrone,Chiara Riva,Ekaterina Rogaeva,Owen A. Ross,Wataru Satake,Peter A. Silburn,Peter A. Silburn,Jessie Theuns,Tatsushi Toda,Hiroyuki Tomiyama,Ryan J. Uitti,Karin Wirdefeldt,Zbigniew K. Wszolek,Thomas Gasser,Rejko Krüger +45 more
TL;DR: This large association study for the SPR gene revealed no association for PD worldwide, however, taking the initial mapping of the PARK3 into account, the role of a population-specific effect warrants consideration in future studies.
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Valproate induces epigenetic modifications in lymphomonocytes from epileptic patients.
Lucio Tremolizzo,Jacopo C. DiFrancesco,Virginia Rodriguez-Menendez,Chiara Riva,Elisa Conti,Gloria Galimberti,Claudio Ruffmann,Carlo Ferrarese +7 more
TL;DR: It is suggested that the epigenetic properties of VPA expressed on PBMC at these concentrations might be operative in different tissues, with possible implications for the field of neuropsychiatric disorders.
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Nonfibrillar Abeta 1-42 inhibits glutamate uptake and phosphorylates p38 in human fibroblasts
Chiara Zoia,Chiara Riva,Valeria Isella,Paola Proserpio,Alessandro Terruzzi,Silvia Arban,Domenico Salerno,Valeria Cassina,Francesco Mantegazza,Lucio Tremolizzo,Carlo Ferrarese +10 more
TL;DR: The results suggest that nonfibrillar Abeta1–42 downregulates glutamate transporters activity interfering with p38-activation and mitochondrial stress, and modulating complex kinase signaling pathway might represent a future therapeutic target in AD.
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