Chiara Lico
ENEA
37 Papers
102 Citations
Chiara Lico is an academic researcher from ENEA. The author has contributed to research in topics: Potato virus X & Biology. The author has an hindex of 14, co-authored 32 publications. Previous affiliations of Chiara Lico include Biotec.
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Papers
Lutein is needed for efficient chlorophyll triplet quenching in the major LHCII antenna complex of higher plants and effective photoprotection in vivo under strong light
Luca Dall'Osto,Chiara Lico,Jean Alric,Giovanni Giuliano,Michel Havaux,Roberto Bassi,Roberto Bassi +6 more
TL;DR: It is concluded that zeaxanthin is effective in photoprotection of plants lacking lutein due to the multiple effects of zeAXanthin in photOProtection, including ROS scavenging and direct quenching of Chl fluorescence by binding to the L2 allosteric site of Lhc proteins.
Viral vectors for production of recombinant proteins in plants.
TL;DR: The principal plant viral‐based production strategies and the latest plant viral expression systems are described, with a particular focus on the variety of proteins produced and their applications.
Plant-produced potato virus X chimeric particles displaying an influenza virus-derived peptide activate specific CD8+ T cells in mice.
Chiara Lico,Camillo Mancini,Paola Italiani,Camilla Betti,Diana Boraschi,Eugenio Benvenuto,Selene Baschieri +6 more
TL;DR: The experiments demonstrated that CVPs activate ASNENMTEM-specific CD8+ T cells and represent the proof of concept that well-designed plant virus carriers of epitopes produced in plant can reasonably be used into peptide vaccine formulations aimed to activate cell-mediated immune responses.
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Peptide display on Potato virus X: molecular features of the coat protein-fused peptide affecting cell-to-cell and phloem movement of chimeric virus particles.
Chiara Lico,Floriana Capuano,Giovanni Renzone,Marcello Donini,Carla Marusic,Andrea Scaloni,Eugenio Benvenuto,Selene Baschieri +7 more
TL;DR: The analysis of infection progression induced by the different constructs enabled identification of two important structural features of the fused peptide, namely tryptophan content and isoelectric point, critically affecting the formation of PVX CVPs and virus movement through the plant.
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The Two-Faced Potato Virus X: From Plant Pathogen to Smart Nanoparticle.
TL;DR: Due to the versatile moods, PVX holds promise to become an interesting nanomaterial, in view to create the widest possible arsenal of new “bio-inspired” devices to face evolving issues in biomedicine and beyond.