Chiara Gentili
University of Genoa
55 Papers
465 Citations
Chiara Gentili is an academic researcher from University of Genoa. The author has contributed to research in topics: Cartilage & Chondrocyte. The author has an hindex of 27, co-authored 50 publications. Previous affiliations of Chiara Gentili include National Cancer Research Institute & University of Pennsylvania.
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Papers
Cartilage and Bone Extracellular Matrix
Chiara Gentili,Ranieri Cancedda +1 more
TL;DR: Homeostasis of cartilage and bone is maintained by complex mechanisms controlling turnover and remodeling of ECM, and ECM should be considered a dynamic network of molecules secreted by cells that in turn regulate cell behavior by modulating their proliferation and differentiation.
258
p38/NF-kB-dependent expression of COX-2 during differentiation and inflammatory response of chondrocytes.
TL;DR: Investigation of the expression pathway of the inflammation‐related enzyme Cyclooxygenase‐2 (COX‐2) during differentiation and inflammatory response of the chondrocytic cell line MC615 indicates that in chONDrocytes, COX‐ 2 is expressed via p38 activation/NF‐kB recruitment during both differentiation andinflammatory response.
175
A Cell-free Scaffold-based Cartilage Repair Provides Improved Function Hyaline-like Repair at One year
TL;DR: The cell-free PGA-hyaluronan scaffold combined with PRP leads to cartilage repair and improved patient-reported outcomes (KOOS) during 12 months of followup.
Amniotic liquid derived stem cells as reservoir of secreted angiogenic factors capable of stimulating neo-arteriogenesis in an ischemic model.
Teodelinda Mirabella,Michele Cilli,Sebastiano Carlone,Ranieri Cancedda,Ranieri Cancedda,Chiara Gentili,Chiara Gentili +6 more
TL;DR: The concept that stem cell-secreted mediators can guide the tissue repair by stimulating or recruiting host reparative cells is asserted, thus preventing the capillary loss and the tissue necrosis of distal muscles.
109
Development of articular cartilage: what do we know about it and how may it occur?
TL;DR: A sequela of events is proposed that may subtend the process of determination and emergence of articular chondrocytes during limb synovial joint development.
86