Chiara Chiellini
University of Pisa
13 Papers
124 Citations
Chiara Chiellini is an academic researcher from University of Pisa. The author has contributed to research in topics: Adipose tissue & White adipose tissue. The author has an hindex of 11, co-authored 13 publications.
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Papers
Characterization of the long pentraxin PTX3 as a TNFα-induced secreted protein of adipose cells
Anissa Abderrahim-Ferkoune,Olivier Bezy,Chiara Chiellini,Margherita Maffei,Paul A. Grimaldi,Frédéric Bonino,Naima Moustaid-Moussa,Fabio Pasqualini,Alberto Mantovani,Gérard Ailhaud,Ez-Zoubir Amri +10 more
TL;DR: PTX3 appears as a TNFalpha-induced protein that provides a new link between chronic low-level inflammatory state and obesity.
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Serum haptoglobin: a novel marker of adiposity in humans.
Chiara Chiellini,Ferruccio Santini,Alessandro Marsili,Piero Berti,A Bertacca,Caterina Pelosini,Giovanna Scartabelli,E Pardini,J López-Soriano,R Centoni,Annamaria Ciccarone,Luca Benzi,Paolo Vitti,S. Del Prato,Aldo Pinchera,Margherita Maffei +15 more
TL;DR: Serum Hp constitutes a novel marker of adiposity in humans, and the adipose tissue likely contributes to determine its levels, as assessed by dual-energy x-ray absorptiometry.
Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFα
Chiara Chiellini,A Bertacca,Silvia E. Novelli,Cem Z. Görgün,Annamaria Ciccarone,Antonio Giordano,Haiyan Xu,Alexander Soukas,Mario Costa,Daniele Gandini,Roberto Dimitri,Pietro Bottone,P. Cecchetti,Ennia Pardini,Lucia Perego,Renzo Navalesi,Franco Folli,Luca Benzi,Saverio Cinti,Jeffrey M. Friedman,Gökhan S. Hotamisligil,Margherita Maffei +21 more
TL;DR: It is demonstrated that haptoglobin expression in WAT is increased in obesity in rodents and TNFα is an important signal for this regulation.
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Gene expression in ductus arteriosus and aorta: comparison of birth and oxygen effects
Mario Costa,Silvia Barogi,Nicholas D. Socci,Debora Angeloni,Margherita Maffei,Barbara Baragatti,Chiara Chiellini,Emanuela Grasso,Flavio Coceani +8 more
TL;DR: It is concluded that several agents, including ANG II as novel effector, promote functional closure of DA, but only ET-1 is causally coupled with oxygen, and oxygen has no role in processes for permanent closure.
Continually high insulin levels impair Akt phosphorylation and glucose transport in human myoblasts.
A Bertacca,Annamaria Ciccarone,P Cecchetti,Barbara Vianello,Incoronata Laurenza,Margherita Maffei,Chiara Chiellini,Stefano Del Prato,Luca Benzi +8 more
TL;DR: Continuous exposure of cultured myoblasts to high insulin levels induces a persistent up-regulation of IR, IRS1, and PI3K activity associated with the demodulation of insulin signaling, which may contribute to the derangement insulin-signaling pathway states of hyperinsulinemia such as obesity and type 2 diabetes.
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