Chiara Agrati
National Institutes of Health
223 Papers
927 Citations
Chiara Agrati is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Immune system & Medicine. The author has an hindex of 31, co-authored 167 publications. Previous affiliations of Chiara Agrati include Bernhard Nocht Institute for Tropical Medicine & Sapienza University of Rome.
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Papers
Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells
Eleonora Cimini,Concetta Castilletti,Alessandra Sacchi,Rita Casetti,Veronica Bordoni,Antonella Romanelli,Federica Turchi,Federico Martini,Nicola Tumino,Emanuele Nicastri,Angela Corpolongo,Antonino Di Caro,Gary P. Kobinger,Alimuddin Zumla,Maria Rosaria Capobianchi,Giuseppe Ippolito,Chiara Agrati +16 more
TL;DR: Study of the phenotype and functionality of T-cells in patients with acute ZIKV and Dengue viral (DENV) infections and their role in the protection and/or pathogenesis needs to be clarified provides new knowledge on the immune response profile during self-limited infection.
Fibrogenic signals persist in DAA-treated HCV patients after sustained virological response.
Claudia Montaldo,Michela Terri,Veronica Riccioni,Cecilia Battistelli,Veronica Bordoni,Gianpiero D'Offizi,Maria Giulia Prado,Flavia Trionfetti,Tiziana Vescovo,Eleonora Tartaglia,Raffaele Strippoli,Chiara Agrati,Marco Tripodi +12 more
TL;DR: In this paper, structural analysis of extracellular vesicle modifications was performed by qPCR, label-free liquid chromatography-mass spectrometry and western blot.
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UPLC–MS/MS method for the simultaneous quantification of sofosbuvir, sofosbuvir metabolite (GS-331007) and daclatasvir in plasma of HIV/HCV co-infected patients
Stefania Notari,Massimo Tempestilli,Gabriele Fabbri,Raffaella Libertone,Andrea Antinori,Adriana Ammassari,Chiara Agrati +6 more
TL;DR: An UPLC-MS/MS method allowing the simultaneous quantification of sofosbuvir, GS-331007 and daclatasvir in plasma samples was developed and validated and was sensitive, specific, robust, and time-saving.
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Persistent Spike-specific T cell immunity despite antibody reduction after 3 months from SARS-CoV-2 BNT162b2-mRNA vaccine
Chiara Agrati,Concetta Castilletti,Delia Goletti,Alessandra Sacchi,Veronica Bordoni,Davide Mariotti,Stefania Notari,Giulia Matusali,Silvia Meschi,Linda Petrone,Alessandra Aiello,Saeid Najafi Fard,Chiara Farroni,Francesca Colavita,Daniele Lapa,S. Leone,Alessandro Agresta,Maria Rosaria Capobianchi,Giuseppe Ippolito,Francesco Vaia,Vincenzo Puro,Eleonora Cimini,Eleonora Tartaglia,Rita Casetti,Germana Grassi,Flavia Cristofanelli,Andrea Capri,Annapaola Santoro,Nicoletta Orchi,Aurora Bettini,Massimo Francalancia,Eliana Specchiarello +31 more
TL;DR: The long lasting cell-mediated immune response after 3 months from vaccination highlight its importance in the maintaining of specific immunity able to expand again to fight eventual new antigen encountering.
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Innate T-cell immunity in HIV infection: the role of Vgamma9Vdelta2 T lymphocytes.
Fabrizio Poccia,Marie-Lise Gougeon,Chiara Agrati,C. Montesano,F. Martini,C. D. Pauza,Paul Fisch,Marianne Wallace,Miroslav Malkovsky +8 more
TL;DR: The potent antiviral activities of Vgamma9Vdelta2 T cells may help to contain viral spread during acute HIV infection and/or to prevent the establishment of viral persistence in HIV-infected patients.
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