Chiako Farshadfar
Islamic Azad University
7 Papers
2 Citations
Chiako Farshadfar is an academic researcher from Islamic Azad University. The author has contributed to research in topics: Virtual screening & Chemistry. The author has an hindex of 2, co-authored 6 publications.
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Papers
Novel potential inhibitor discovery against tyrosyl-tRNA synthetase from Staphylococcus aureus by virtual screening, molecular dynamics, MMPBSA and QMMM simulations
Chiako Farshadfar,Adriano Mollica,Fatemeh Rafii,Akbar Noorbakhsh,Mozhgan Nikzad,Seyed Hamid Seyedi,Fatemeh Abdi,Somayeh Abbasi Verki,Sako Mirzaie +8 more
TL;DR: Molecular modelling investigation, along with QM/MM studies, suggests that ZINC59675144 has impressive properties as a potential inhibitor of YRS, and also can be utilised as lead compound for further improvements.
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Blockage of the Monoamine Oxidase by a Natural Compound to Overcome Parkinson’s Disease via Computational Biology
TL;DR: It is indicated that ZINC00261335 is a suitable MAO-B inhibitor and a great candidate for more laboratory studies and the ADME study (lipophilicity, drug similarity and pharmacokinetic parameters) was revealed, which is acceptable for human use.
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Structure-based virtual screening, molecular docking and dynamics studies of natural product and classical inhibitors against human dihydrofolate reductase
Elnaz Hosseininezhadian Koushki,Solmaz Abolghasemi,Adriano Mollica,Mojtaba Aghaeepoor,Seyedeh Sara Moosavi,Chiako Farshadfar,Bayazid Hasanpour,Babisandz Feyzi,Fatemeh Abdi,Sako Mirzaie +9 more
TL;DR: QMMM data suggested that a structure with ZINC ID of ZINC31169388 has a stronger interaction with DHFR active site and could be a favorable candidacy for biological assessment and additional advanced improvement.
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The SARS-Cov-2 Proliferation Blocked by a Novel and Potent Main Protease Inhibitor via Computer-aided Drug Design
Sepideh Shayan,Shahab Jamaran,Rafee Habib Askandar,Arian Rahimi,Azam Elahi,Chiako Farshadfar,Noeman Ardalan +6 more
TL;DR: It is suggested that ZINC31157475 can potentially treat COVID-19 by inhibition of the 3CLp, however, in-vitro and in- vivo study is essential for approval of this suggestion.
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Structural screening into the recognition of a potent inhibitor against non-structural protein 16: a molecular simulation to inhibit SARS-CoV-2 infection.
Seyed Hamid Seyedi,Mohammad Shakib Alhagh,Mehran Ahmadizad,Noeman Ardalan,Elnaz Hosseininezhadian Koushki,Chiako Farshadfar,Barzan Amjadi +6 more
TL;DR: Sarma et al. as discussed by the authors used the ZINC and PubChem databases to screen some chemical compounds regarding Sinefungin as a control inhibitor for the CoVID-19 infection.
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