Chester W. Brown
University of Tennessee Health Science Center
62 Papers
271 Citations
Chester W. Brown is an academic researcher from University of Tennessee Health Science Center. The author has contributed to research in topics: Biology & Adipogenesis. The author has an hindex of 31, co-authored 61 publications. Previous affiliations of Chester W. Brown include St. Jude Children's Research Hospital & Baylor College of Medicine.
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Papers
Genetic analysis of the mammalian transforming growth factor-beta superfamily.
TL;DR: This review attempts to collate and integrate the extensive body of in vivo mammalian studies produced over the last decade that revealed that TGF-β superfamily ligands, receptors, SMADs, and upstream and downstream regulators function in diverse developmental and physiological pathways.
Research capacity. Enabling the genomic revolution in Africa
Charles N. Rotimi,Akin Abayomi,Alash'le Abimiku,Victoria Adabayeri,Clement Adebamowo,Ezekiel Adebiyi,Adebowale D. Ademola,Adebowale Adeyemo,Dwomoa Adu,Dissou Affolabi,Godfred Agongo,Samuel Ajayi,Sally N Akarolo-Anthony,Rufus Akinyemi,Albert Akpalu,Marianne Alberts,Orlando Alonso Betancourt,Ahmed M. Alzohairy,Gobena Ameni,Olukemi K. Amodu,Gabriel Anabwani,Kristian G. Andersen,Fatiu A Arogundade,Oyedunni Arulogun,Danny Asogun,Rasheed Bakare,Naby Balde,Mary Lynn Baniecki,Christine Beiswanger,Alia Benkahla,Lara Bethke,M Boehnke,Vincent Boima,James Brandful,Andrew Brooks,Frank C. Brosius,Chester W. Brown,Bruno Bucheton,David T. Burke,Barrington G. Burnett,Stacy Carrington-Lawrence,Nadia Carstens,John Chisi,Alan Christoffels,Richard S. Cooper,Heather J. Cordell,Nigel J. Crowther,Talishiea Croxton,Jantina de Vries,Leslie Derr,Peter Donkor,Seydou Doumbia,Audrey Duncanson,Ivy Ekem,Ahmed El Sayed,Mark E Engel,John Enyaru,Dean Everett,Faisal M. Fadlelmola,Eyitayo Fakunle,Kenneth H. Fischbeck,Anne Fischer,Onikepe A. Folarin,Junaid Gamieldien,Robert F. Garry,Simani Gaseitsiwe,Rasheed Gbadegesin,Anita Ghansah,Maria Y. Giovanni,Parham Goesbeck,F. Xavier Gómez-Olivé,Donald S. Grant,Ravnit Grewal,Mark S. Guyer,Neil A. Hanchard,Christian T. Happi,Scott Hazelhurst,Branwen J. Hennig,Christiane Hertz-Fowler,Winston Hide,Friedhelm Hilderbrandt,Christopher Hugo-Hamman,Muntaser E. Ibrahim,Regina James,Yasmina Jaufeerally-Fakim,Carolyn Jenkins,Ute Jentsch,Pan Pan Jiang,Moses Joloba,Victor Jongeneel,Fourie Joubert,Mukthar Kader,Kathleen Kahn,Pontiano Kaleebu,Saidi Kapiga,Samar K. Kassim,Ishmael Kasvosve,Jonathan K. Kayondo,Bernard Keavney,Adeodata Kekitiinwa,Sheik Humarr Khan,Paul L. Kimmel,Mary Claire King,Robert Kleta,Mathurin Koffi,Jeffrey B. Kopp,Matthias Kretzler,Judit Kumuthini,Samuel Kyobe,Catherine Kyobutungi,Daniel T. Lackland,Karen A. Lacourciere,Guida Landouré,Rita T. Lawlor,Thomas Lehner,Maia Lesosky,Naomi S. Levitt,Katherine Littler,Zané Lombard,Jeanne F. Loring,Sylvester Leonard Lyantagaye,Annette MacLeod,Ebony B. Madden,Chengetai R. Mahomva.,Julie Makani,Manmak Mamven,Marape Marape,Graeme Mardon,Patricia A. Marshall,Darren P. Martin,Daniel K. Masiga,Robin Mason,Michael Mate-Kole,Enock Matovu,Mary T Mayige,Mary T Mayige,Bongani M. Mayosi,Jean Claude Mbanya,Sheryl A. McCurdy,Mark I. McCarthy,Helen McIlleron,Seth O. McLigeyo,Corrine Merle,Ana Olga Mocumbi,Charles Mondo,John V. Moran,Ayesha A. Motala,Marva Moxey-Mims,Sununguko Wata Mpoloka,Chisomo L. Msefula,Thuli Mthiyane,Nicola Mulder,Gebregziabher Mulugeta,Dieuodonne Mumba,John Musuku,Mo Nagdee,Oyekanmi Nash,Daouda Ndiaye,Anh Quynh Nguyen,Mark P. Nicol,Oathokwa Nkomazana,Shane A. Norris,Betty Nsangi,Alexander K. Nyarko,Moffat Nyirenda,Eileen Obe,Reginald Obiakor,Abraham Oduro,Solomon F. Ofori-Acquah,Okechukwu S Ogah,S.W.O. Ogendo,Kwaku Ohene-Frempong,Akinlolu O. Ojo,T O Olanrewaju,John Oli,Charlotte Osafo,Odile Ouwe Missi Oukem-Boyer,Bruce Ovbiagele,Andrew Owen,Mayowa O. Owolabi,Lukman Owolabi,Ellis Owusu-Dabo,Guillaume Paré,Rulan S. Parekh,Hugh-G. Patterton,Margaret B. Penno.,Jane Peterson,Rembert Pieper,Jacob Plange-Rhule,Martin R. Pollak,Julia Puzak,Rajkumar Ramesar,Michèle Ramsay,Rebekah S. Rasooly,Shiksha Reddy,Pardis C. Sabeti,Kwamena W. Sagoe,Tunde Salako,Oumar Samassekou,Manjinder S. Sandhu,Manjinder S. Sandhu,Manjinder S. Sandhu,Osman Sankoh,Fred Stephen Sarfo,Marie Sarr,Gasnat Shaboodien,Issa Sidibe,Gustave Simo,Martin Simuunza,Liam Smeeth,Eugene Sobngwi,Himla Soodyall,Hermann Sorgho,Oumou Sow Bah,Sudha Srinivasan,Dan J. Stein,Ezra Susser,Carmen Swanepoel,Godfred Tangwa,Andrew Tareila,Özlem Tastan Bishop,Bamidele O. Tayo,Nicki Tiffin,Halidou Tinto,Ekaete Tobin,Stephen Tollman,Mahamadou Traoré,Marsha Treadwell,Jennifer L. Troyer,Masego Tsimako-Johnstone,Vincent Tukei,Ifeoma Ulasi,Nzovu Ulenga,Beverley van Rooyen,Ablo Prudence Wachinou,Salina P. Waddy,Alisha N. Wade,Misaki Wayengera,James A. G. Whitworth,Louise Wideroff,Cheryl A. Winkler,Sarah Winnicki,Ambroise Wonkam,Mengistu Tadase Yewondwossen,Nathan L. Yozwiak,Heather J. Zar +245 more
TL;DR: If the dearth of genomics research involving Africans persists, the potential health and economic benefits emanating from genomic science may elude an entire continent.
Mitochondrial dysfunction in obesity.
Juan C. Bournat,Chester W. Brown +1 more
TL;DR: The review highlights recent findings regarding the functions of mitochondria in adipocytes, providing an understanding of their central roles in regulating substrate metabolism, energy expenditure, disposal of reactive oxygen species, and in the pathophysiology of obesity and insulin resistance, as well as roles in the mechanisms that affect adipogenesis and mature adipocyte function.
Use of Exome Sequencing for Infants in Intensive Care Units: Ascertainment of Severe Single-Gene Disorders and Effect on Medical Management
Linyan Meng,Linyan Meng,Mohan Pammi,Anirudh Saronwala,Pilar L. Magoulas,Pilar L. Magoulas,Andrew R. Ghazi,Francesco Vetrini,Jing Zhang,Weimin He,Avinash V. Dharmadhikari,Chunjing Qu,Patricia A. Ward,Patricia A. Ward,Alicia Braxton,Alicia Braxton,Swetha Narayanan,Swetha Narayanan,Xiaoyan Ge,Mari Tokita,Teresa Santiago-Sim,Hongzheng Dai,Theodore Chiang,Hadley Stevens Smith,Mahshid S. Azamian,Laurie Robak,Bret L. Bostwick,Bret L. Bostwick,Christian P. Schaaf,Christian P. Schaaf,Lorraine Potocki,Lorraine Potocki,Fernando Scaglia,Fernando Scaglia,Carlos A. Bacino,Carlos A. Bacino,Neil A. Hanchard,Neil A. Hanchard,Michael F. Wangler,Michael F. Wangler,Daryl A. Scott,Daryl A. Scott,Chester W. Brown,Jianhong Hu,John W. Belmont,Lindsay C. Burrage,Lindsay C. Burrage,Brett H. Graham,Vernon R. Sutton,Vernon R. Sutton,William J. Craigen,William J. Craigen,Sharon E. Plon,Sharon E. Plon,James R. Lupski,Arthur L. Beaudet,Richard A. Gibbs,Donna M. Muzny,Marcus J. Miller,Marcus J. Miller,Xia Wang,Xia Wang,Magalie S. Leduc,Magalie S. Leduc,Rui Xiao,Rui Xiao,Pengfei Liu,Pengfei Liu,Chad A. Shaw,Magdalena Walkiewicz,Magdalena Walkiewicz,Weimin Bi,Weimin Bi,Fan Xia,Fan Xia,Brendan Lee,Christine M. Eng,Christine M. Eng,Yaping Yang,Yaping Yang,Seema R. Lalani,Seema R. Lalani,Seema R. Lalani +82 more
TL;DR: Exome sequencing is a powerful tool for the diagnostic evaluation of critically ill infants with suspected monogenic disorders in the neonatal and pediatric intensive care units and its use has a notable effect on clinical decision making.
Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing
Christina Camell,Jil Sander,Olga Spadaro,Aileen Lee,Kim Y. Nguyen,Allison Wing,Emily L. Goldberg,Yun-Hee Youm,Chester W. Brown,John D. Elsworth,Matthew S. Rodeheffer,Joachim L. Schultze,Joachim L. Schultze,Vishwa Deep Dixit +13 more
TL;DR: This study reveals that targeting neuro-immunometabolic signalling between the sympathetic nervous system and macrophages may offer new approaches to mitigate chronic inflammation-induced metabolic impairment and functional decline.