Chenguang Wang
Johns Hopkins University
245 Papers
1.1K Citations
Chenguang Wang is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Cyclin D1 & Biology. The author has an hindex of 63, co-authored 211 publications. Previous affiliations of Chenguang Wang include Nankai University & University of Washington.
Chat about Author
Papers
Risk haplotype analysis for bovine paratuberculosis
TL;DR: A significant risk haplotype within the CARD15 gene was detected to trigger genetic effects on paratuberculosis infection in an overdominace manner, and will provide scientific guidance about the selection and prediction of resistance types in bovines.
16
Propensity score-integrated power prior approach for augmenting the control arm of a randomized controlled trial by incorporating multiple external data sources
Nelson Lu,Chenguang Wang,Wei-Chen Chen,Heng Li,Changhong Song,Ram C. Tiwari,Yunling Xu,Lilly Q. Yue +7 more
TL;DR: In this paper, a propensity score-integrated power prior approach is developed to augment the control arm of a two-arm randomized controlled trial (RCT) with subjects from multiple external data sources such as real-world data (RWD) and historical clinical studies containing subject-level outcomes and covariates.
15
A computational approach for functional mapping of quantitative trait loci that regulate thermal performance curves.
TL;DR: A statistical model for dissecting thermal performance curves into individual quantitative trait loci (QTL) with the aid of a genetic linkage map and results from simulation studies suggest that the model displays favorable statistical properties and can be robust in practical genetic applications.
A Causal Model for Joint Evaluation of Placebo and Treatment-Specific Effects in Clinical Trials
TL;DR: The model highlights the importance of measuring and incorporating patient treatmentality and suggests that each treatment group should be considered a separate observational study with a patient's treatmentality playing the role of an uncontrolled exposure.
14
Oncogenic transformation of normal breast epithelial cells co-cultured with cancer cells
TL;DR: It is shown that cancer cell-secreted factors were sufficient to induce cancerous transformation of normal cells, and transformed cells were resistant to radiation treatment, providing new insights into mechanisms underlying therapeutic resistance.
13