Chenguang Wang
Johns Hopkins University
245 Papers
1.1K Citations
Chenguang Wang is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Cyclin D1 & Biology. The author has an hindex of 63, co-authored 211 publications. Previous affiliations of Chenguang Wang include Nankai University & University of Washington.
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Papers
Imaging Spontaneous MMTVneu Transgenic Murine Mammary Tumors: Targeting Metabolic Activity Versus Genetic Products
Mathew L. Thakur,Devakumar Devadhas,Kaijun Zhang,Richard G. Pestell,Chenguang Wang,Peter McCue,Eric Wickstrom +6 more
TL;DR: This investigation determined the ability of 1 of the peptide analogs, 64Cu-TP3805, to detect BC in MMTVneu mice using 18F-FDG as a gold standard and identified all malignant lesions unequivocally that overexpressed the VPAC1 oncogene surface product.
Multivalent human papillomavirus l1 DNA vaccination utilizing electroporation
Kihyuck Kwak,Rosie Jiang,Subhashini Jagu,Joshua W. Wang,Chenguang Wang,Neil D. Christensen,Richard B.S. Roden +6 more
TL;DR: In vivo electroporation for multivalent codon-optimized human papillomavirus (HPV) L1 and L2 DNA vaccination requires spatial separation of individual type L1 DNA vaccines, and durable protective antibody titers were achieved for each type.
Functional mapping of genotype-environment interactions for soybean growth by a semiparametric approach.
Qin Li,Zhongwen Huang,Meng Xu,Chenguang Wang,Junyi Gai,Youjun Huang,Xiaoming Pang,Rongling Wu +7 more
TL;DR: The principle of using composite functional mapping to estimate the effects of QTL-environment interactions on growth trajectories by parametrically modeling the tested QTL in a marker interval and nonparametrically modeled the markers outside the interval as co-factors is reported.
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Caveolin-1 overexpression enhances androgen-dependent growth and proliferation in the mouse prostate
Kelly G. Bryant,Jeanette Camacho,Jean-Francois Jasmin,Chenguang Wang,Sankar Addya,Mathew C. Casimiro,Paolo Fortina,Sucharitha Balasubramaniam,Karen E. Knudsen,Roland Schwarting,Michael P. Lisanti,Isabelle Mercier +11 more
TL;DR: It is demonstrated that Cav-1 overexpression favors androgen-regulated responses and enhances processes involved in transcription, cell cycle progression and protein synthesis, and could serve as a novel model for studying AR-regulated pathways involved in prostate growth and proliferation.
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A computational framework for the inheritance pattern of genomic imprinting for complex traits
TL;DR: A computational framework for analyzing the magnitude of genetic imprinting and its transgenerational inheritance mode is presented and will enable geneticists to identify and map imprinted quantitative trait loci and dictate a comprehensive atlas of developmental and epigenetic mechanisms related to Genetic imprinting.
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