Chenglin Mo
University of Texas at Arlington
31 Papers
36 Citations
Chenglin Mo is an academic researcher from University of Texas at Arlington. The author has contributed to research in topics: Skeletal muscle & Myocyte. The author has an hindex of 10, co-authored 27 publications. Previous affiliations of Chenglin Mo include University of Texas at Austin & University of Missouri–Kansas City.
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Papers
Prostaglandin E2 promotes proliferation of skeletal muscle myoblasts via EP4 receptor activation
Chenglin Mo,Ruonan Zhao,Julian Vallejo,Orisa J. Igwe,Lynda F. Bonewald,Lori A Wetmore,Marco Brotto +6 more
TL;DR: PGE2 signaling via the EP4 receptor regulates myogenesis by promoting myoblast proliferation and blocking this receptor results in increased ROS production in myoblasts, confirmed by cell cycle analysis and the gene expression of cell cycle regulators.
107
METTL21C is a potential pleiotropic gene for osteoporosis and sarcopenia acting through the modulation of the NF-κB signaling pathway.
Jian Huang,Yi-Hsiang Hsu,Chenglin Mo,Eduardo Abreu,Douglas P. Kiel,Lynda F. Bonewald,Maxrco Brotto,David Karasik +7 more
TL;DR: The results suggest that Mettl21c might exert its bone‐muscle pleiotropic function via the regulation of the NF‐κB signaling pathway, which is critical for bone and muscle homeostasis.
98
Crosstalk Between MLO-Y4 Osteocytes and C2C12 Muscle Cells Is Mediated by the Wnt/β-Catenin Pathway
Jian Huang,Sandra Romero-Suarez,Nuria Lara,Chenglin Mo,Simon Kaja,Leticia Brotto,Sarah L. Dallas,Mark L. Johnson,Katharina Jähn,Lynda F. Bonewald,Marco Brotto +10 more
- 01 Oct 2017
TL;DR: The data show that in vitro and ex vivo, osteocytes can stimulate myogenesis and enhance muscle contractile function and suggest that Wnts could be mediators of bone to muscle signaling, likely via modulation of intracellular Ca2+ signaling and the Wnt/ β‐Catenin pathway.
94
Muscle-specific inositide phosphatase (MIP/MTMR14) is reduced with age and its loss accelerates skeletal muscle aging process by altering calcium homeostasis.
Sandra Romero-Suarez,Jinhua Shen,Leticia Brotto,Todd Hall,Chenglin Mo,Héctor H. Valdivia,Jon Andresen,Michael J. Wacker,Thomas M. Nosek,Cheng-Kui Qu,Marco Brotto +10 more
- 25 Aug 2010
TL;DR: A MIP knockout (MIPKO) animal model is developed and found that MIPKO mice were more susceptible to exercise-induced muscle damage, a trademark of muscle functional changes in older subjects, and offers a new avenue for the investigation of MIP roles in skeletal muscle function and as a potential therapeutic target to treat aging sarcopenia.
Quantification of aminobutyric acids and their clinical applications as biomarkers for osteoporosis.
Zhiying Wang,Liangqiao Bian,Chenglin Mo,Hui Shen,Lan Juan Zhao,Kuan Jui Su,Maciej Kukula,Jauh Tzuoh Lee,Daniel W. Armstrong,Robert R. Recker,Joan M. Lappe,Lynda F. Bonewald,Hong-Wen Deng,Marco Brotto +13 more
- 22 Jan 2020
TL;DR: In this article, the authors developed a quick, accurate, and sensitive screening method for aminobutyric acid isomers and enantiomers yielding correlations with bone mineral density (BMD) and osteoporotic fracture.