Cheng Teng
Wenzhou Medical College
7 Papers
7 Citations
Cheng Teng is an academic researcher from Wenzhou Medical College. The author has contributed to research in topics: Oxidative stress & Unfolded protein response. The author has co-authored 3 publications.
Chat about Author
Papers
Echinacoside Upregulates Sirt1 to Suppress Endoplasmic Reticulum Stress and Inhibit Extracellular Matrix Degradation In Vitro and Ameliorates Osteoarthritis In Vivo
Zhen Lin,Cheng Teng,Libin Ni,Zhao Zhang,Xinlei Lu,Junsheng Lou,Libo Wang,Yuxin Wang,Wenhao Chen,Xiaolei Zhang,Lin Zhongke +10 more
TL;DR: Wang et al. as discussed by the authors explored the specific role of Echinacoside in the occurrence and development of osteoarthritis and its underlying mechanism in vivo and in vitro, and demonstrated the effectiveness of ECH in suppressing ER stress and restoring ECM metabolism in vitro.
Orientin downregulating oxidative stress-mediated endoplasmic reticulum stress and mitochondrial dysfunction through AMPK/SIRT1 pathway in rat nucleus pulposus cells in vitro and attenuated intervertebral disc degeneration in vivo
Zhao Zhang,Jingtao Wu,Cheng Teng,Jinquan Wang,Jiapei Yu,Chen Jin,Libo Wang,Long Wu,Zhen Lin,Ziping Yu,Zhongke Lin +10 more
TL;DR: Ori treatment in vitro increased SIRT1/AMPK in NPCs, maintained ECM and ER balance and decreased oxidative stress (OS) response, and partly unveil the underlying mechanisms of Ori in IVDD.
27
Ginsenoside Rb1 inhibits ferroptosis to ameliorate hypoxic-ischemic brain damage in neonatal rats.
Min Zhang,Wei-Hua Lin,Xiaoyue Tao,Wei Zhou,Zhenyu Zhang,Shuqing Jin,Haojie Zhang,Cheng Teng,Jianghu Zhu,Xiaoling Guo,Zhenlang Lin +10 more
TL;DR: Wang et al. as discussed by the authors investigated the neuroprotective effects of GsRb1 on HIE, and illuminated the potential mechanism, which showed that Gsrb1 and the ferroptosis inhibitor liproxstatin-1 (Lip-1) could significantly restore System Xc activity and antioxidant levels as well as inhibit lipid oxidation levels and inflammatory index levels of HIBD and OGD.
12
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
TL;DR: Wang et al. as discussed by the authors demonstrated that Eicosapentaenoic acid (EPA) can promote autophagy, reduce ECM degradation and ER stress in vitro, thereby reducing cell apoptosis, and the protective effects of EPA in an IDD-rat model in vivo.
8
Fucoxanthin ameliorates endoplasmic reticulum stress and inhibits apoptosis and alleviates intervertebral disc degeneration in rats by upregulating Sirt1.
Cheng Teng,Jingtao Wu,Zhao Zhang,Jinquan Wang,Ye Yang,Chengji Dong,Long Wu,Zhen Lin,Yuezheng Hu,Jing Wang,Xiaolei Zhang,Zhong-Qing Lin +11 more
TL;DR: The study demonstrates the effect of FX on improving IDD in vivo and in vitro, suggesting that FX may be a potential drug for the treatment of IDD.
3