Cheng Jin
Chinese Academy of Sciences
68 Papers
383 Citations
Cheng Jin is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Aspergillus fumigatus & Conidiation. The author has an hindex of 19, co-authored 68 publications. Previous affiliations of Cheng Jin include Guangxi University & Academia Sinica.
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Papers
A molecular vision of fungal cell wall organization by functional genomics and solid-state NMR
Arnab Chakraborty,Liyanage D. Fernando,Wenxia Fang,Malitha C. Dickwella Widanage,Pingzhen Wei,Cheng Jin,Thierry Fontaine,Jean-Paul Latgé,Tuo Wang +8 more
TL;DR: In this paper, the cell wall structure of a fungal pathogen Aspergillus fumigatus and four mutants depleted of major structural polysaccharides was compared.
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Glycosylphosphatidylinositol (GPI) anchor is required in Aspergillus fumigatus for morphogenesis and virulence.
TL;DR: The analysis of the mutants showed that a completely blocking of the GPI anchor synthesis in A. fumigatus led to cell wall defect, abnormal hyphal growth, rapid conidial germination and aberrant conidiation, and a reduced virulence in immunocompromised mice.
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O-Mannosyltransferase 1 in Aspergillus fumigatus (AfPmt1p) is crucial for cell wall integrity and conidium morphology, especially at an elevated temperature.
TL;DR: In this article, the PMT gene family of the human fungal pathogen Aspergillus fumigatus was identified and characterized, where only one member of each PMT subfamily, Afpmt1, AfPmt1p, AfPMt2, and AfPmt4, is present in A fumarigatus.
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Protein Glycosylation in Aspergillus fumigatus Is Essential for Cell Wall Synthesis and Serves as a Promising Model of Multicellular Eukaryotic Development
TL;DR: The present paper implies that the investigation of glycosylation in A. fumigatus is not only vital for elucidating the mechanism of fungal cell wall synthesis, which will benefit the design of new antifungal therapies, but also helps to understand the role of protein glycosYLation in the development of multicellular eukaryotes.
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Decalin-Containing Tetramic Acids and 4-Hydroxy-2-pyridones with Antimicrobial and Cytotoxic Activity from the Fungus Coniochaeta cephalothecoides Collected in Tibetan Plateau (Medog)
Junjie Han,Congcong Liu,Congcong Liu,Li Li,Hui Zhou,Li Liu,Li Bao,Qian Chen,Fuhang Song,Lixin Zhang,Erwei Li,Ling Liu,Yunfei Pei,Cheng Jin,Yanfen Xue,Wen-Bing Yin,Yanhe Ma,Hongwei Liu +17 more
TL;DR: In the light of a co-occurrence of 3-acyl tetramic acids and biogenetically related pyridine alkaloids, the biosynthetic pathway for 1-12 was postulated.
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