Chenfei Wang
Shanghai Jiao Tong University
6 Papers
8 Citations
Chenfei Wang is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Medicine & Autophagy. The author has an hindex of 1, co-authored 1 publications.
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Papers
TRPV1-Mediated Microglial Autophagy Attenuates Alzheimer’s Disease-Associated Pathology and Cognitive Decline
TL;DR: TRPV1 agonist capsaicin decreased amyloid and phosphorylated tau pathology and reversed memory deficits by promoting microglia activation, metabolism, and autophagy in 3xTg mice, indicating that TRPV 1 was a potential therapeutic target for AD.
A breakdown in microglial metabolic reprogramming causes internalization dysfunction of α-synuclein in a mouse model of Parkinson’s disease
Jia Qian Lu,Chenfei Wang,Xin Cheng,Rui-Xian Wang,Xuejiao Yan,Peng-Yu He,Hong-Zhuan Chen,Zhihua Yu +7 more
TL;DR: In this article , the role of transient receptor potential vanilloid type 1 (TRPV1) channels in microglial autophagocytosis in Parkinson's disease was investigated.
TRPV1 regulates ApoE4-disrupted intracellular lipid homeostasis and decreases synaptic phagocytosis by microglia
TL;DR: In this paper , the authors show that ApoE4 leads to lipid metabolism dysregulation in microglia, resulting in enhanced MHC-II-dependent antigen presentation and T-cell activation.
A breakdown in microglial metabolic reprogramming causes internalization dysfunction of α-synuclein in a mouse model of Parkinson’s disease
Jia Lu,Chenfei Wang,Xin Cheng,Rui-Xian Wang,Xue-Jing Yan,Peng-Yu He,Hongzhuan Chen,Zhihua Yu +7 more
TL;DR: In this paper , the role of transient receptor potential vanilloid type 1 (TRPV1) channels in microglial autophagocytosis in Parkinson's disease was investigated.
Interleukin-10-Overexpressing Mesenchymal Stromal Cells Induce a Series of Regulatory Effects in the Inflammatory System and Promote the Survival of Endotoxin-Induced Acute Lung Injury in Mice Model
TL;DR: It is demonstrated that IL-10-MSCs offered superior protection against LPS-induced ALI when given before or at the time of ALI induction, and significantly increased the frequencies of IL- 10-expressing T cells and B cells.