Chen Xi
Sun Yat-sen University
6 Papers
44 Citations
Chen Xi is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Apoptosis & Oxidative stress. The author has an hindex of 4, co-authored 5 publications.
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Papers
Triptolide-induced oxidative stress involved with Nrf2 contribute to cardiomyocyte apoptosis through mitochondrial dependent pathways.
Jie Zhou,Chen Xi,Wenwen Wang,Xinglu Fu,Liang Jinqiang,Yuwen Qiu,Jin Jin,Jingfen Xu,Zhiying Huang +8 more
TL;DR: The results suggest that TP induces cardiotoxicity in vivo and in vitro via oxidative stress, which was associated with down regulated Nrf2 activation, and the mitochondria-mediated apoptotic signaling pathway.
86
Endoplasmic reticulum stress mediates aristolochic acid I-induced apoptosis in human renal proximal tubular epithelial cells.
Shaohua Zhu,Yan Wang,Jing Jin,Cuiwen Guan,Mei Li,Chen Xi,Zizhang Ouyang,Meiwan Chen,Yuwen Qiu,Min Huang,Zhiying Huang +10 more
TL;DR: The results suggest that the ER stress response is involved in apoptosis induced by AAI in HK-2 cells, thus offering a new insight into the nephrotoxicity of AAI.
46
Autophagy plays an important role in triptolide-induced apoptosis in cardiomyocytes.
TL;DR: Results suggest that TP-induced cell death can be modified by autophagy, and induction of autophagic by rapamycin may be a potential cardioprotective role against TP- induced cardiotoxicity by facilitating removal of dysfunctional mitochondria.
43
Local and systemic effects of IDH mutations on primary glioma patients
TL;DR: In this article , the effects of IDH mutations on primary glioma patients are illustrated using retrospective analysis, immunecell infiltration analysis, meta-analysis, and immunohistochemistry assay.