Risk Factors for Shunt Dependency after Aneurysmal Subarachnoid Hemorrhage: A Meta-Analysis including 25 Years of Data

The Expression of MIR17HG Protein as a Potential Therapeutic Target in Meningioma.

Leonurine hydrochloride-a new drug for the treatment of menopausal syndrome: Synthesis, estrogen-like effects and pharmacokinetics

The invention relates to transformer wiring terminal manufacturing and forming processing equipment which comprises a supporting device, a bearing device, a fixing device and a cutting device. The fixing device is installed on the left side of the supporting device, the bearing device is installed in the middle of the supporting device, and the cutting device is installed on the right side of thesupporting device. According to the technical scheme of the invention, problems that during the grooving process of a wiring terminal, an existing wiring terminal machining device does not have supporting effect on the wiring terminal, the wiring terminal easily deforms in the machining process, and the quality of finished wiring terminals is reduced are easily caused, and the problems that an existing wiring terminal machining device mostly adopts a pressure fixing or clamping mode, the wiring terminal is fixed to the device, shaking is likely to happen, and the machining precision is reducedcan be solved.

Transformer wiring terminal manufacturing, forming and processing equipment

Sporadic multiple intracranial meningioma does not infer worse patient outcomes: results from a case control study

/pdf/letter-to-the-editor-is-there-any-relationship-between-438kvotq4j.pdf

Letter to the Editor. Is there any relationship between estrogen receptor/progesterone receptor status and recurrence of meningioma?

/pdf/letter-to-the-editor-multiple-meningiomas-3ygtk14mdo.pdf

Letter to the Editor. Multiple meningiomas.

The invention discloses a transformer low-voltage pot head connection assembly with high pollution-resistant capability. The transformer low-voltage pot head connection assembly with high pollution-resistant capability comprises a sleeve, wherein the sleeve is matched with a binding post of a low-voltage pot head in a sleeved way and has plasticity, a broken groove is formed in one side of the sleeve and is used for cutting a side wall of the sleeve to form two broken walls corresponding to the broken groove, clamping arms are fixedly arranged on outer walls of the sleeve corresponding to the broken walls and outwards extend along the broken walls, corresponding clamping holes are formed in the two clamping arms, clamping bolts are inserted into the clamping holes and are used for clamping the sleeve onto the binding post by the clamping arms, a wiring board is fixedly arranged on an outer wall of the other side of the sleeve and upwards extends, and the wiring board is connected with a cable by a locking device. The transformer low-voltage pot head connection assembly has the advantages of reasonable structure, large contact area, small contact resistance, good cleanness, working stability and reliability, long service lifetime, long maintenance period and low operation cost, is convenient to install a wire and is suitably used in a place with serious air pollution, an overheat or burnt accident is not liable to happen, dust is not liable to paste, and threaded post burn-up or an open-circuit and phase-losing accident caused by heat generation due to loosing of a vibration nut after the transformer low-voltage pot head connection assembly is used for a long time is prevented.

Transformer low-voltage pot head connection assembly with high pollution-resistant capability

TO THE EDITOR: We read with great interest the research by Fujii et al.4 (Fujii Y, Muragaki Y, Maruyama T, et al: Threshold of the extent of resection for WHO Grade III gliomas: retrospective volumetric analysis of 122 cases using intraoperative MRI. J Neurosurg [epub ahead of print September 8, 2017. DOI: 10.3171/2017.3.JNS162383]) regarding extent of resection for WHO grade III gliomas. The article is well written, and the authors have demonstrated that extent of resection (EOR) of T2-weighted high–signal intensity lesions (T2-EOR) was one of the most important prognostic factors for patients with anaplastic astrocytoma (AA) and anaplastic oligoastrocytoma (AOA) and an especially significant survival advantage was seen with T2-EOR ≥ 53%. We highly commend the authors for performing this interesting study because these helpful results would be useful to make a balanced treatment decision planning to prolong patient survival. However, after a detailed analysis of this article, we would like to highlight 3 important issues that it raises. First, 122 patients with newly diagnosed WHO grade III gliomas had undergone intraoperative MRI–guided resection during the period from March 2000 to December 2011. In the article’s Results section, however, it is unclear how many patients underwent a second reoperation for recurrent WHO Grade III gliomas after initial resection. It would be helpful to the reader to know whether reoperation for recurrent WHO grade III gliomas can improve overall survival. Unfortunately, there is no evidence to date that supports this hypothesis. However, there exists a relationship between reoperation and overall survival of patients with recurrent glioblastoma.2,7 In the report by Tully et al. of 204 patients with de novo glioblastoma, 49 patients (24%) with recurrent glioblastoma underwent reoperation, and the median overall survival in the reoperation group was 20.1 months, compared with 9.0 months in the no-reoperation group (p = 0.001), demonstrating that reoperation was associated with longer overall survival.7 Coburger et al. revealed similar results from their study of 170 surgeries for glioblastoma, showing that repeated surgery for recurrent disease has a beneficial effect on overall survival.2 Second, the authors concluded that a significant survival advantage was associated with resection of 53% or more of the preoperative T2-weighted high–signal intensity volume in patients with AA and AOA. But if the tumor is located near an eloquent area, is it safe for resection of 53% or more of the preoperative T2-weighted high–signal intensity volume? Some studies indicate that intraoperative cortical and subcortical stimulation can be used to identify functional areas or tracts and to guide surgical removal of gliomas in eloquent areas.1,3 This approach may be able to maximize the extent of resection while minimizing the risk of permanent deficit.1,3 Furthermore, awake craniotomy as a special method can prevent motor deficits during the resection of gliomas adjacent to eloquent cortex. Ghinda et al. reported that combined awake craniotomy and intraoperative MRI was safe and efficient, allowing maximal safe resection of eloquent area gliomas with possible subsequent benefits in terms of overall survival and progression-free survival.5 However, what is the exact maximal safe resection for gliomas near eloquent areas? A few studies have indicated that a safe margin of 8 mm should be maintained between the limits of resection and the pyramidal tracts.8,9 So it was probably wise to tailor the resection of gliomas adjacent to eloquent cortex according to intraoperative electrophysiological investigation, manifestation of intraoperative tasks for awake surgery, and intraoperative MRI, rather than only resection of 53% or more of the T2-weighted high–signal intensity lesions. Third, we noted that the authors did not analyze data from patients who simultaneously presented with IDH1/2 mutation and 1p/19q co-deletion. The authors concluded that T2-EOR was not significantly different in patients with AO at any cutoff value, which may be associated with 1p/19q co-deletions and response to chemotherapy.4 We wonder whether T2-EOR was also not significantly different for survival in patients with glioma with the IDH1/2 mutation and 1p/19q co-deletion? Kawaguchi et al. investigated the impact of gross-total resection (GTR) in their series of 124 patients with WHO grade III glioma. They found that patients with tumors with IDH1/2 mutation and 1p/19q co-deletion had better outcomes, and that GTR or lack of GTR had no significant effect on the survival of such patients.6 We expect that the authors further validated the relationship between T2-EOR and survival in patients with WHO grade III glioma with IDH1/2 mutation and 1p/19q co-deletion. This may influence therapeutic strategies and clinical decisions.

/pdf/letter-to-the-editor-resection-for-who-grade-iii-gliomas-77ckjlmp5z.pdf

Letter to the Editor. Resection for WHO Grade III gliomas.

The invention discloses a telegraph-pole centering device for electric power repairing. The telegraph-pole centering device comprises a transversely-arranged base. A back limiting device and a front limiting device are arranged at the two ends of the base. A swinging barrel capable of swinging back and forth is hinged to the interior of a supporting section of the base. A supporting device is inserted into the swinging barrel and locked to the upper middle section of a telegraph pole through a hinged locking device capable of vertically swinging. The power input end of the supporting device is in transmission connection with a power device through a bendable transmission hose. A handle is further fixedly arranged on a supporting base. An outwards-extending protective cover is fixedly arranged at the inner end of the handle. The telegraph-pole centering device has the advantages that soil and stone on the normal-position side of the telegraph pole can be rapidly excavated, dust disoperation can be prevented, the telegraph pole can be rapidly centered, time and labor are saved, fixing is firm, the size is small, carrying is convenient, one person can independently center the telegraph pole, centering efficiency is high, and the telegraph pole can be prevented from being broken off.

Telegraph-pole centering device for electric power repairing

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