Dietary habits that include an excess of added sugars have been strongly associated with an increased risk of obesity, heart disease, diabetes, and tooth decay. With this association in view, modern food systems aim to replace added sugars with low calorie sweeteners, such as polyols. Polyols are generally not carcinogenic and do not trigger a glycemic response. Furthermore, owing to the absence of the carbonyl group, they are more stable compared to monosaccharides and do not participate in Maillard reactions. As such, since polyols are stable at high temperatures, and they do not brown or caramelize when heated. Therefore, polyols are widely used in the diets of hypocaloric and diabetic patients, as well as other specific cases where controlled caloric intake is required. In recent years, erythritol and mannitol have gained increased importance, especially in the food and pharmaceutical industries. In these areas, research efforts have been made to improve the productivity and yield of the two polyols, relying on biotechnological manufacturing methods. The present review highlights the recent advances in the biotechnological production of erythritol and mannitol and summarizes the benefits of using the two polyols in the food and pharmaceutical industries.

Recent advances in the biotechnological production of erythritol and mannitol

Potential benefits of Lactobacillus plantarum as probiotic and its advantages in human health and industrial applications: A review

Mannitol Production by Heterofermentative Lactic Acid Bacteria: a Review

Isolation, characterisation and exploitation of lactic acid bacteria capable of efficient conversion of sugars to mannitol.

Identification of Lactobacillus brevis using a species-specific AFLP-derived marker.

Lactobacillus brevis 3-A5 was isolated and expected to produce mannitol efficiently by regulating pH in batch and fed-batch fermentations. In 48 h batch fermentations with free and constant pH, the optimal pH for cell growth and mannitol production in the first 24 h of incubation was 5.5, whereas that for mannitol production in the second 24 h of incubation was 4.5. To achieve high cell density and mannitol yield simultaneously, a dual-stage pH control strategy was proposed based on the kinetic analysis of mannitol production. The pH value was controlled at 5.5 for the first 12 h of fermentation and subsequently shifted to 4.5 until the fermentation was completed. Under dual-stage pH control fermentation, a 103 g/L yield of mannitol with a volumetric production rate of 3.7 g/L/h was achieved after 28 h. The dual-stage pH control fed-batch fermentation strategy was further developed to improve mannitol yield, wherein the yield increased by 109 % to 215 g/L after 98 h of fermentation. This value is the highest yield of mannitol ever reported using L. brevis.

Improvement of mannitol production by Lactobacillus brevis mutant 3-A5 based on dual-stage pH control and fed-batch fermentations.

The invention provides a method for producing fructooligosaccharid and high fructose syrup by using an immobilized enzyme. The method comprises the following steps of: immobilizing inulase by using a three-step method of oxidation-immobilization-reduction; and producing the fructooligosaccharid and the high fructose syrup by utilizing the immobilized enzyme. Due to the adoption of immobilization technology, the activity yield of enzyme is high and the stability of the immobilized enzyme is high; and the enzyme can be recovered and repeatedly utilized by producing the fructooligosaccharid and the high fructose syrup by using the immobilized enzyme so as to reduce production cost.

Method for producing fructooligosaccharid and high fructose syrup by using immobilized enzyme

The invention discloses a preparation process of chitin oligose, which comprises the following steps: adding an acetylation reagent in the chitosan oligosaccharide solution with the concentration of 0.1%-50%, and reacting for 1 minute to 48 hours at the temperature of 0 DEG C to 100 DEG C to obtain the chitin oligose after the amino is acetylized selectively. The prepared chitin oligose has the following characteristics that the molecular weight is 400-7000 Dalton (Da), the degree of the amino acetylation is 85%-100%, and the hydroxyl is not acetylized. By adopting the preparation process disclosed by the invention, the mass production of the chitin oligose is achieved, thereby developing new medicines, functional food, food addictives, feed addictives, biological pesticides, plant growth promoters, plant stress resistance agents and the like.

Preparation process of chitin oligose

The invention relates to an antioxidant and application thereof, and relates to application of chlorella polysaccharides in preparation of plant green pesticides and food additives. The chlorella polysaccharides are a group of polysaccharides with a molecular weight of 10.6-13.6kDa, and are prepared from water-insoluble chlorella part (algal residue) by enzymolysis, deproteinization and alcohol precipitation, and the monosaccharide is mainly composed of glucose, galactose, arabinose, fucose and rhamnose. The chlorella polysaccharides can significantly improve plant cell antioxidase (SOD, POD and CAT) (superoxide dismutase, peroxidase and catalase) and in-vitro hydroxyl free radical clearance rate, reducing power, DPPH (1,1-diphenyl-2-picrylhydrazyl radical) clearance rate and other activity, and can be used as a plant growth regulator and a natural food additive.

Antioxidant and application thereof

The invention relates to a method for efficient preparation of mannose. Specifically, phosphomolybdate is adopted as a solid catalyst for efficient catalysis of glucose conversion to prepare mannose. The technology provided by the invention has the advantages of wide source and cheap raw materials, simple process, simple separation, reusable catalyst, and lower production cost, thus having very strong competitiveness.

Preparation method for mannose

Handle everyday research tasks with reliable, citation-backed results

Your personal Research Agent to handle research tasks with citation-backed results

Popular Tasks used by Researchers

How can I help with your research?

Meet SciSpace

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

Chen Wei

Author Tools

Chat about Author