Chen Ge
Shenzhen University
7 Papers
Chen Ge is an academic researcher from Shenzhen University. The author has contributed to research in topics: Chemistry & Viscosity. The author has an hindex of 3, co-authored 4 publications.
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Papers
Nucleus-Targeted Organoiridium-Albumin Conjugate for Photodynamic Cancer Therapy.
Pingyu Zhang,Huaiyi Huang,Samya Banerjee,Guy J. Clarkson,Chen Ge,Cinzia Imberti,Peter J. Sadler +6 more
TL;DR: Ir1‐HSA mainly accumulated in the nucleus of living cancer cells and showed remarkable photocytotoxicity against a range of cancer cell lines and tumor spheroids, while remaining non‐toxic to normal cells and normal cell sp Heroids, even after photo‐irradiation.
114
A "Self-Checking" pH/Viscosity-Activatable NIR-II Molecule for Real-Time Evaluation of Photothermal Therapy Efficacy.
Benhao Li,Hengke Liu,Yaling He,Mengyao Zhao,Chen Ge,Muhammad Rizwan Younis,Peng Huang,Xiaoyuan Shawn Chen,Jing Li +8 more
TL;DR: A second near-infrared (NIR-II) self-checking molecule, LET-1052, for acidic tumor microenvironment (TME) turn-on photothermal therapy (PTT), followed by viscosity based therapeutic efficacy evaluation by itself in two independent channels, denoted as "self-checking" strategy.
61
Isomeric Ir(III) complexes for tracking mitochondrial pH fluctuations and inducing mitochondrial dysfunction during photodynamic therapy
Haijie Chen,Chen Ge,Huiqun Cao,Xuepeng Zhang,Ling Zhang,Linhai Jiang,Pingyu Zhang,Qianling Zhang +7 more
TL;DR: Interestingly, these pH-responsive probes can be utilized to monitor the change in mitochondrial pH and mitochondrial damage during photodynamic therapy (PDT), which provides a convenient method for the in situ monitoring of therapeutic effects and the assessment of treatment outcomes.
20
Novel Worm-like Micelles for Hydrochloride Doxorubicin Delivery: Preparation, Characterization, and In Vitro Evaluation
TL;DR: In this paper , a novel acitretin-based surfactant (ACMeNa) with good solid stability to encapsulate DOX to form micelles (ACM-DOX) was presented.
A "Self‐Checking" pH/Viscosity‐Activatable NIR‐II Molecule for Real‐Time Evaluation of Photothermal Therapy Efficacy
Benhao Li,Hengke Liu,Yaling He,Mengyao Zhao,Chen Ge,Muhammad Rizwan Younis,Peng Huang,Xiaoyuan Shawn Chen,Jing Li +8 more
TL;DR: In this paper , a second near-infrared self-checking molecule, LET-1052, was protonated and turned on NIR-II absorption for photothermal therapy (PTT) under 1064 nm laser irradiation.