Charlotta Dabrosin
Linköping University
66 Papers
612 Citations
Charlotta Dabrosin is an academic researcher from Linköping University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 29, co-authored 57 publications. Previous affiliations of Charlotta Dabrosin include McMaster University.
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Papers
Broad targeting of angiogenesis for cancer prevention and therapy
Zongwei Wang,Charlotta Dabrosin,Xin Yin,Mark M. Fuster,Alexandra Arreola,W. Kimryn Rathmell,Daniele Generali,Ganji Purnachandra Nagaraju,Bassel F. El-Rayes,Domenico Ribatti,Yi Charlie Chen,Kanya Honoki,Hiromasa Fujii,Alexandros G. Georgakilas,Somaira Nowsheen,Amedeo Amedei,Elena Niccolai,Amr Amin,S. Salman Ashraf,Bill Helferich,Xujuan Yang,Gunjan Guha,Dipita Bhakta,Maria Rosa Ciriolo,Katia Aquilano,Sophie Chen,Dorota Halicka,Sulma I. Mohammed,Asfar S. Azmi,Alan Bilsland,W. Nicol Keith,Lasse Jensen,Lasse Jensen +32 more
TL;DR: 10 important aspects of tumor angiogenesis and the pathological tumor vasculature which would be well suited as targets for anti-angiogenic therapy are identified and 10 plant-derived compounds could be combined to constitute a broader acting and more effective inhibitory cocktail at doses that would not be likely to cause excessive toxicity.
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Resveratrol induces apoptosis and inhibits angiogenesis in human breast cancer xenografts in vivo.
TL;DR: The potential use of resveratrol as a chemotherapeutic agent in breast cancers is supported by the observed significantly lower tumor growth, decreased angiogenesis, and increased apoptotic index in ERalpha- ERbeta+ MDA-MB-231 tumors in resver atrol-treated nude mice compared with controls.
370
Designing a broad-spectrum integrative approach for cancer prevention and treatment
Keith I. Block,Charlotte Gyllenhaal,Leroy Lowe,Amedeo Amedei,A.R.M. Ruhul Amin,Amr Amin,Katia Aquilano,Jack L. Arbiser,Jack L. Arbiser,Alexandra Arreola,Alla Arzumanyan,S. Salman Ashraf,Asfar S. Azmi,Fabian Benencia,Dipita Bhakta,Alan Bilsland,Anupam Bishayee,Stacy W. Blain,Penny B. Block,Chandra S. Boosani,Thomas E. Carey,Amancio Carnero,Marianeve Carotenuto,Stephanie C. Casey,Mrinmay Chakrabarti,Rupesh Chaturvedi,Georgia Zhuo Chen,Helen Chen,Sophie Chen,Yi Charlie Chen,Beom K. Choi,Maria Rosa Ciriolo,Helen M. Coley,Andrew Collins,Marisa Connell,Sarah Crawford,Colleen S. Curran,Charlotta Dabrosin,Giovanna Damia,Santanu Dasgupta,Ralph J. DeBerardinis,William K. Decker,Punita Dhawan,Anna Mae Diehl,Jin-Tang Dong,Q. Ping Dou,Janice E. Drewa,Eyad Elkord,Bassel F. El-Rayes,Mark A. Feitelson,Dean W. Felsheru,Lynnette R. Ferguson,Carmela Fimognari,Gary L. Firestone,Christian Frezza,Hiromasa Fujii,Mark M. Fuster,Daniele Generali,Alexandros G. Georgakilas,Frank Gieseler,Michael Gilbertson,Michelle F. Green,Brendan Grue,Gunjan Guhal,Dorota Halicka,William G. Helferich,Petr Heneberg,Patricia Hentosh,Matthew D. Hirschey,Lorne J. Hofseth,Randall F. Holcombe,Kanya Honoki,Hsue-Yin Hsu,Gloria S. Huang,Lasse Jensen,Lasse Jensen,Wen Guo Jiang,Lee W. Jones,Phillip Karpowicz,W. Nicol Keith,Sid P. Kerkar,Gazala Khan,Mahin Khatami,Young Hee Ko,Omer Kucuk,Rob J. Kulathinal,Nagi B. Kumar,Byoung S. Kwon,Anne Leb,Michael A. Leab,Ho Young Lee,Terry Lichtor,Liang Tzung Lin,Jason W. Locasale,Balakrishna L. Lokeshwar,Valter D. Longo,Costas A. Lyssiotis,Karen L. MacKenzie,Meenakshi Malhotra,Maria Marino,María L. Martínez-Chantar,Ander Matheu,Christopher Maxwellx,Eoin McDonnell,Alan K. Meeker,Mahya Mehrmohamadi,Kapil Mehta,Gregory A. Michelotti,Ramzi M. Mohammad,Sulma I. Mohammed,D. James Morré,Irfana Muqbil,Vinayak Muralidharcq,Vinayak Muralidharcq,Michael P. Murphy,Ganji Purnachandra Nagaraju,Rita Nahta,Elena Niccolai,Somaira Nowsheen,Carolina Panis,Francesco Pantano,Virginia R. Parslow,Graham Pawelec,Peter L. Pedersen,Brad Poore,Deepak Poudyal,Satya Prakash,Mark E. Prince,Lizzia Raffaghello,Jeffrey C. Rathmell,W. Kimryn Rathmell,Swapan K. Ray,Jörg Reichrath,Sarallah Rezazadeh,Domenico Ribatti,Luigi Ricciardiello,R. Brooks Robeydf,R. Brooks Robeydf,Francis Rodierdh,H.P. Vasantha Rupasinghe,Gian Luigi Russo,Elizabeth P. Ryan,Abbas Samadi,Isidro Sánchez-García,Andrew James Sanders,Daniele Santini,Malancha Sarkar,Tetsuro Sasada,Neeraj K. Saxena,Rodney E. Shackelford,H. M. C. Shantha Kumara,Dipali Sharma,Dong M. Shin,David Sidransky,Markus D. Siegelin,Emanuela Signori,Neetu Singh,Sharanya Sivanand,Daniel Sliva,Carl Smythe,Carmela Spagnuolo,Diana M. Stafforini,John Stagg,Pochi R. Subbarayan,Tabetha Sundin,Wamidh H. Talib,Sarah K. Thompson,Phuoc T. Tran,Hendrik Ungefroren,Matthew G. Vander Heiden,Vasundara Venkateswaran,Dass S. Vinay,Panagiotis J. Vlachostergios,Zongwei Wang,Kathryn E. Wellen,Richard L. Whelan,Eddy S. Yang,Huanjie Yang,Xujuan Yang,Paul Yaswen,Clement G. Yedjou,Xin Yin,Jiyue Zhu,Massimo Zollo +183 more
TL;DR: An international task force of 180 scientists was assembled to explore the concept of a low-toxicity "broad-spectrum" therapeutic approach that could simultaneously target many key pathways and mechanisms, and results suggest that a broad-spectrums approach should be feasible from a safety standpoint.
276
•Journal Article
Tamoxifen inhibits secretion of vascular endothelial growth factor in breast cancer in vivo.
Stina Garvin,Charlotta Dabrosin +1 more
TL;DR: It is shown for the first time that tamoxifen decreased extracellular VEGF in vivo in solid MCF-7 tumors in nude mice, and it is illustrated that microdialysis is a viable method that may be applied in human breast tissue to detect soluble V EGF in situ released by the tumor.
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Therapeutic Effect of Angiostatin Gene Transfer in a Murine Model of Endometriosis
TL;DR: Gene therapy with angiogenic inhibitors is a highly effective treatment for endometriosis, even in a host with preserved estrogen levels, however, local or targeted delivery of the gene must be considered to avoid prolonged systemic effects and impaired ovarian function.