Changlong Wang

TL;DR: A novel microcapsule-based formulation for high-performance cancer vaccinations with special self-healing feature provides a mild and efficient paradigm for antigen microencapsulation that effectively increase the antigen utilization, improve the antigen presentation, and activate antigen presenting cells.

TL;DR: This work provides a strong empirical foundation that nanovaccine researchers should position delivery mode near the top of their considerations for the experimental design, which should speed up nanvaccine development and facilitate efficient selection of appropriate delivery modes in the clinic.

TL;DR: In this paper, an arsenic-containing nano-drug and a preparation method for its preparation is described. But the preparation method comprises the following steps: adding ferrous salt into a denucleated ferritin solution, then adding a trivalent arsenic salt solution, forming ferrum-oxygen-arsenic compound nanoparticles in the inner cavity by in-situ precipitation of tri-valent arsenate salt and ferriferous fine nuclei in the Ferritin inner cavity.

TL;DR: In this paper, a ferritin-based nanomedicine, As@Fn, was designed to bound leukaemia cells with very high affinity, and efficiently delivered cytotoxic AsIII into a large diversity of leukemia cell lines and patient cells.