Changjin Lee
Seoul National University
12 Papers
61 Citations
Changjin Lee is an academic researcher from Seoul National University. The author has contributed to research in topics: SWI/SNF & Chromatin remodeling. The author has an hindex of 10, co-authored 12 publications.
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Papers
Srg3, a Mouse Homolog of Yeast SWI3, Is Essential for Early Embryogenesis and Involved in Brain Development
Joong K. Kim,Sung-Oh Huh,Heonsik Choi,Keesook Lee,Dongho Shin,Changjin Lee,Ju-Suk Nam,Hyun Kim,Heekyoung Chung,Han W. Lee,Sang D. Park,Rho Hyun Seong +11 more
TL;DR: It is demonstrated that Srg3 is essential for early embryogenesis and plays an important role in the brain development of mice and that exencephaly is caused by the failure in neural fold elevation, resulting in severe brain malformation.
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SRG3, a core component of mouse SWI/SNF complex, is essential for extra-embryonic vascular development.
Daehee Han,Shin Jeon,Dong Hyun Sohn,Changjin Lee,Sangil Ahn,Won Kyu Kim,Heekyoung Chung,Rho Hyun Seong +7 more
TL;DR: It is indicated that SRG3 is required for angiogenesis and visceral endoderm development in the yolk sac and Mutant mice deficient in Srg3 expression are peri-implantation lethal.
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DNA aptamers against the receptor binding region of hemagglutinin prevent avian influenza viral infection
Seung Kwan Choi,Changjin Lee,Kwang-Soo Lee,Soo Young Choe,In Pil Mo,Rho Hyun Seong,Seokmann Hong,Sung Ho Jeon +7 more
TL;DR: Cloned cDNA fragment encoding the entire globular region of viral hemagglutinin of the H9N2 type avian influenza virus is cloned and it is suggested that the aptamers can recognize and inhibit the binding of the virus to target receptors required for the penetration of host cells.
Twist2 regulates CD7 expression and galectin-1-induced apoptosis in mature T-cells.
Han Seok Koh,Changjin Lee,Kwang-Soo Lee,Eun Jung Park,Rho Hyun Seong,Seokmann Hong,Sung Ho Jeon +6 more
TL;DR: It is concluded that upregulation of Twist2 increases the resistance to galectin-1-mediated-apoptosis, which may have significant implications for the progression of some T-cells into tumors such as Sezary cells.
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The SWI/SNF Chromatin-remodeling Complex Modulates Peripheral T Cell Activation and Proliferation by Controlling AP-1 Expression
TL;DR: It is shown that the SWI/SNF complex regulates cytokine production and proliferation of T cells and that mice that constitutively expressed the SWF complex in T cells were much more susceptible to experimentally induced autoimmune encephalomyelitis than the normal mice were.
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