Celia M. T. Greenwood
McGill University
301 Papers
2.3K Citations
Celia M. T. Greenwood is an academic researcher from McGill University. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 51, co-authored 275 publications. Previous affiliations of Celia M. T. Greenwood include Cancer Care Ontario & Ontario Institute for Cancer Research.
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Papers
Software Application Profile: RVPedigree: a suite of family-based rare variant association tests for normally and non-normally distributed quantitative traits
TL;DR: RVPedigree implements a suite of programs facilitating genome-wide analysis of association between a quantitative trait and autosomal region-based genetic variation, and includes calculation of kinship matrices, various options for coping with non-normality, and three different ways of estimating statistical significance.
On Statistical Power for Case-Control Host Genomic Studies of COVID-19
Yu-Chung Lin,Jennifer D. Brooks,Shelley B. Bull,Shelley B. Bull,Celia M. T. Greenwood,Celia M. T. Greenwood,Rayjean J. Hung,Rayjean J. Hung,Jerald F. Lawless,Andrew M. Paterson,Lei Sun,Lisa J. Strug +11 more
TL;DR: It is demonstrated why studying susceptibility to SARS-CoV-2 infection could be futile at the early stages of the pandemic and can aid in the interpretation of genetic findings emerging in the literature and guide the design of future host genetic studies.
A Bayesian nonparametric method for model evaluation: application to genetic studies
TL;DR: In this paper, a nonparametric Bayesian method for model assessment was proposed for gene-disease relationship, and the authors demonstrate the advantages of this approach particularly when the sample size is small and/or the true model is non-linear.
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Novel approaches to discovery of biomarkers in rheumatoid arthritis: comment on the article by Oswald et al.
Marie Hudson,Murray Baron,Ines Colmegna,Sasha Bernatsky,Kathleen Klein Oros,Tomi Pastinen,Celia M. T. Greenwood +6 more
TL;DR: Two memory subsets of memory T lymphocytes with distinct homing potentials and effector functions in rheumatoid arthritis, and the role of anti-CD8 therapy in inducing disease amelioration.
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Multivariate association test for rare variants controlling for cryptic and family relatedness
TL;DR: This work considers association testing between a set of rare variants and multiple phenotypes in family‐based designs and derives a vector of score statistics, whose joint distribution is approximated using a copula to express the correlations among the phenotypes and between related individuals.
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