Celeste Hutton
Centre for Addiction and Mental Health
2 Papers
Celeste Hutton is an academic researcher from Centre for Addiction and Mental Health. The author has contributed to research in topics: Internal medicine & Translocator protein. The author has an hindex of 2, co-authored 2 publications.
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Papers
Translocator Protein Distribution Volume Predicts Reduction of Symptoms During Open-Label Trial of Celecoxib in Major Depressive Disorder.
Sophia Attwells,Elaine Setiawan,Pablo Rusjan,Cynthia Xu,Celeste Hutton,Dorsa Rafiei,Benjamin Varughese,Alan Kahn,Stephen J. Kish,Neil Vasdev,Sylvain Houle,Jeffrey H. Meyer,Jeffrey H. Meyer +12 more
TL;DR: In this article, the authors measured the Translocator Protein Total Distribution Volume (TSPO) in the prefrontal cortex (PFC) and anterior cingulate cortex (ACC) to predict reduction of depressive symptoms following open-label celecoxib administration in treatment-resistant major depressive disorder.
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Replicating predictive serum correlates of greater translocator protein distribution volume in brain.
Sophia Attwells,Elaine Setiawan,Alan A. Wilson,Alan A. Wilson,Pablo Rusjan,Laura Miler,Cynthia Xu,Celeste Hutton,Muhammad Ishrat Husain,Stephen J. Kish,Stephen J. Kish,Neil Vasdev,Sylvain Houle,Sylvain Houle,Jeffrey H. Meyer,Jeffrey H. Meyer +15 more
TL;DR: Assessment of threshold serum values to predict highly elevated TSPO VT demonstrated that a positive predictive value (PPV) of 80% was possible while retaining 40% of participant samples and that receiver operating curves (ROC) ranged from 75 to 81%.
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