Cédric Vrignaud
French Institute of Health and Medical Research
5 Papers
18 Citations
Cédric Vrignaud is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Gene & K562 cells. The author has an hindex of 3, co-authored 5 publications.
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Papers
Inherited glycosylphosphatidylinositol defects cause the rare Emm-negative blood phenotype and developmental disorders
Romain Duval,Gaël Nicolas,Alexandra Willemetz,Yoshiko Murakami,Mahmoud Mikdar,Cédric Vrignaud,Hisham Megahed,Jean-Pierre Cartron,Cécile Masson,Samer Wehbi,Berengere Koehl,Marie Hully,Karine Siquier,Nicole Chemlay,Agnès Rötig,Stanislas Lyonnet,Yves Colin,Giulia Barcia,Vincent Cantagrel,Caroline Le Van Kim,Olivier Hermine,Taroh Kinoshita,Thierry Peyrard,Slim Azouzi +23 more
TL;DR: In this article, it was shown that homozygous null alleles of PIGG, a gene involved in GPI modification, are responsible for the rare Emm-negative blood phenotype.
19
Genetic background of the rare Yus and Gerbich blood group phenotypes: homologous regions of the GYPC gene contribute to deletion alleles.
Elise Gourri,Gregory A. Denomme,Yvonne Merki,Erwin A. Scharberg,Cédric Vrignaud,Beat M. Frey,T. Peyrard,Christoph Gassner +7 more
TL;DR: The approach substitutes the serological characterization with a precise genotype approach to identify the rare Yus and Gerbich alleles.
9
CORS (CROM20): A new high-prevalence antigen in the Cromer blood group system
Cédric Vrignaud,Jacques Chiaroni,Elisabeth Durieux-Roussel,Caroline Le Van Kim,Slim Azouzi,Thierry Peyrard +5 more
TL;DR: The identification and characterization of a new Cromer high‐prevalence antigen, named CORS, which carries a c.713G>A substitution in the CD55 gene, resulting in the substitution of glycine 238 into a glutamic acid (p.Gly238Glu).
4
Anticorps anti-privé dans le système RH et maladie hémolytique du nouveau-né?: à propos de 2 cas
Cécile Toly-Ndour,Stéphanie Huguet-Jacquot,F. Pernot,Florence Minier,Céline Goissen,Said Amrouche,Angélique Chauvineau,Mohammed Khalloufi,Cédric Vrignaud,Jérôme Babinet,Vincent Thonier,Thierry Peyrard,Agnès Mailloux,Anne Cortey +13 more
TL;DR: L’identification, the prise en charge et l’information relative a ces cas complexes reposent sur une collaboration etroite entre cliniciens, laboratoires d’immunohematologie et laboratoire de reference.
2
Lack of the multidrug transporter MRP4/ABCC4 defines the PEL-negative blood group and impairs platelet aggregation
Slim Azouzi,Mahmoud Mikdar,Patricia Hermand,Emilie-Fleur Gautier,Virginie Salnot,Alexandra Willemetz,Gaël Nicolas,Cédric Vrignaud,Alexandre Raneri,Patrick Mayeux,Christine Bole-Feysot,Patrick Nitschke,Jean-Pierre Cartron,Yves Colin,Olivier Hermine,Gabriele Jedlitschky,Marc Cloutier,Jessica Constanzo-Yanez,Carole Éthier,Nancy Robitaille,Maryse St-Louis,Caroline Le Van Kim,Thierry Peyrard +22 more
TL;DR: It was shown that loss-of-function mutations in the ABCC4 gene, associated with leukemia outcome, altered the expression of the PEL antigen, which could open a new way toward drug dose adjustment for leukemia treatment.