Catherine K. Foo
University of California, San Francisco
6 Papers
22 Citations
Catherine K. Foo is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Ribosome profiling & Gene expression profiling. The author has an hindex of 5, co-authored 6 publications.
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Papers
The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster.
Ronald P. van Rij,Maria-Carla Saleh,Bassam Berry,Catherine K. Foo,Andrew R. Houk,Christophe Antoniewski,Raul Andino +6 more
TL;DR: The central catalytic component of the RNA-induced silencing complex (RISC), the nuclease Argonaute 2 (Ago-2), is essential for antiviral defense in adult Drosophila melanogaster.
Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster
Joshua G. Dunn,Catherine K. Foo,Nicolette G. Belletier,Elizabeth R. Gavis,Jonathan S. Weissman +4 more
TL;DR: A ribosome profiling assay for Drosophila melanogaster is presented and the first genome-wide experimental analysis of readthrough is provided, demonstrating that readthrough occurs in yeast and humans and providing general mechanisms both to regulate gene expression and function, and to add plasticity to the proteome during evolution.
Identification of Histoplasma capsulatum transcripts induced in response to reactive nitrogen species.
TL;DR: It is proposed that H. capsulatum uses the pathways identified here to cope with RNS-induced damage during pathogenesis as well as other mechanisms involved in iron acquisition, energy production, stress response, protein folding/degradation, DNA repair, and *NO detoxification.
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Radically different amyloid conformations dictate the seeding specificity of a chimeric Sup35 prion.
TL;DR: How conformations determine the specificity of prion transmission is established and a remarkable plasticity to amyloid misfolding is demonstrated.
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Experimental annotation of the human pathogen Histoplasma capsulatum transcribed regions using high-resolution tiling arrays
TL;DR: The first genome-wide studies to experimentally validate the Histoplasma genome annotation are provided, providing critical support for continued investigation into the biology and pathogenesis of H. capsulatum and related fungi.