Catherijne A. J. Knibbe
Leiden University
282 Papers
849 Citations
Catherijne A. J. Knibbe is an academic researcher from Leiden University. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 49, co-authored 242 publications. Previous affiliations of Catherijne A. J. Knibbe include Erasmus University Medical Center & Utrecht University.
Chat about Author
Papers
Intravenous Paracetamol Dosing Guidelines for Pain Management in (pre)term Neonates Using the Paediatric Study Decision Tree.
Paola Mian,Catherijne A. J. Knibbe,Catherijne A. J. Knibbe,Elisa A. M. Calvier,Dick Tibboel,Karel Allegaert,Karel Allegaert +6 more
TL;DR: A loading dose 20mg/kg, followed by 10 mg/kg/6h is recommended for 32-44 weeks' neonates, which is supported by short-term safety, though additional clinical studies are needed to support its safety.
Midazolam Pharmacokinetics in Morbidly Obese Patients Following Semi-Simultaneous Oral and Intravenous Administration: A Comparison with Healthy Volunteers
Margreke J. E. Brill,Anne van Rongen,Aletta P. I. Houwink,Jacobus Burggraaf,Bert van Ramshorst,René M J Wiezer,Eric P.A. van Dongen,Catherijne A. J. Knibbe +7 more
TL;DR: In morbidly obese patients, systemic clearance of midazolam is unchanged, while oral bioavailability is increased, and given the large increase in volumes of distribution, dose adaptations for intravenous midAZolam should be considered.
Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematologic stem cell transplantation.
Imke H. Bartelink,R.G.M. Bredius,Svetlana V. Belitser,Marit M. Suttorp,Marc Bierings,Catherijne A. J. Knibbe,Maarten Egeler,Arjan C. Lankester,Atoine C.G. Egberts,Juliette Zwaveling,Jaap Jan Boelens +10 more
TL;DR: D dose targeting of busulfan to a narrow therapeutic range was found to increase EFS in children, and adding melphalan to optimal bus sulfuran exposure is associated with a high incidence of toxicity.
Optimisation of fluconazole therapy for the treatment of invasive candidiasis in preterm infants
Aline G.J. Engbers,Robert B. Flint,Swantje Voeller,Irwin K M Reiss,Kian D. Liem,Jan-Willem C. Alffenaar,Dick Tibboel,Sinno H.P. Simons,Catherijne A. J. Knibbe,Roger J. M. Brüggemann +9 more
TL;DR: In preterm neonates, fluconazole clearance is best predicted by actual body weight and serum creatinine concentration, so dosing should not only be based on body weight but also on creat inine concentration to achieve optimal exposure in all infants.
Novel Explanted Human Liver Model to Assess Hepatic Extraction, Biliary Excretion and Transporter Function
Lianne J. Stevens,Jeroen Dubbeld,Jason B. Doppenberg,Bart van Hoek,Aswin Menke,Joanne M. Donkers,Abdulnaser Alsharaa,Arjan J de Vries,Wouter H. J. Vaes,Catherijne A. J. Knibbe,E. van de Steeg,Ian P. J. Alwayn +11 more
TL;DR: In this article , the authors developed a physiologically relevant human liver model consisting of normothermic machine perfusion (NMP) of explanted diseased human livers that can assess hepatic extraction, clearance, biliary excretion, and drug-drug interaction (DDI).