Cassidy E. Wideman
University of Guelph
11 Papers
13 Citations
Cassidy E. Wideman is an academic researcher from University of Guelph. The author has contributed to research in topics: Memory consolidation & Medicine. The author has an hindex of 4, co-authored 7 publications.
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Papers
Involvement of classical neurotransmitter systems in memory reconsolidation: Focus on destabilization
TL;DR: The fact that boundary conditions can be overcome in the presence of novelty, providing evidence for the theory that reconsolidation is a mechanism for memory updating is discussed, and a detailed review of the role of classical neurotransmitter systems, including dopamine, serotonin, noradrenaline, glutamate, GABA and acetylcholine, in reconsolidization is explored.
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Dissociable involvement of estrogen receptors in perirhinal cortex-mediated object-place memory in male rats.
Krista A. Mitchnick,Ari L. Mendell,Cassidy E. Wideman,Kristen H. Jardine,Samantha D. Creighton,Anne-Marie Muller,Elena Choleris,Neil J. MacLusky,Boyer D. Winters +8 more
TL;DR: Assessment of the role of 17-βestradiol (E2), ERα, ERβ, GPER, and their downstream signaling pathways, in PRh-mediated object-in-place (OiP) memory in gonadally-intact male rats reveals interesting dissociations between the roles of various ERs.
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Activation of cortical M 1 muscarinic receptors and related intracellular signaling is necessary for reactivation-induced object memory updating
Kristen H. Jardine,Cassidy E. Wideman,Chelsea MacGregor,Cassandra Sgarbossa,Dean Orr,Krista A. Mitchnick,Boyer D. Winters +6 more
TL;DR: A hitherto unacknowledged cognitive function for acetylcholine is demonstrated with important implications for understanding the dynamic nature of long-term memory storage in the normal and aging brain.
The evidence for and against reactivation-induced memory updating in humans and nonhuman animals
TL;DR: In this paper , the authors present a systematic approach to the entire body of evidence, integrating positive and null findings, to yield a comprehensive understanding of the complex and dynamic nature of long-term memory storage and the potential for harnessing modification processes to treat mental disorders driven by pervasive maladaptive memories.
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Fluctuating NMDA Receptor Subunit Levels in Perirhinal Cortex Relate to Their Dynamic Roles in Object Memory Destabilization and Reconsolidation.
TL;DR: In this article, the same dissociable roles of GluN2B and N2A-containing NMDARs in perirhinal cortex (PRh) were demonstrated for object memory destabilization and reconsolidation when boundary conditions are absent.
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