Caroline Pons
French Institute of Health and Medical Research
7 Papers
Caroline Pons is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 2 publications.
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Papers
Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo
Meri K. Tulic,Elisa Cavazza,Yann Cheli,Arnaud Jacquel,Carmelo Luci,Nathalie Cardot-Leccia,Hanene Hadhiri-Bzioueche,Patricia Abbe,Maeva Gesson,Laura Sormani,Claire Regazzetti,Guillaume E. Beranger,Cedric Lereverend,Caroline Pons,Abdallah Khemis,Robert Ballotti,Corine Bertolotto,Stéphane Rocchi,Thierry Passeron +18 more
TL;DR: NK and ILC1 cells are increased in vitiligo patients, and induce melanocyte apoptosis via CXCR3B, which in turn leads to increased priming of T cell responses in cell culture.
A stable hepatitis D virus-producing cell line for host target and drug discovery.
Charlotte Bach,Julie Lucifora,Marion Delphin,Laura Heydmann,Margaux J Heuschkel,Caroline Pons,Kaku Goto,Els Scheers,Catherine Schuster,David Durantel,Frederik Pauwels,Thomas F. Baumert,Eloi R. Verrier +12 more
TL;DR: HuH7-2C8D as discussed by the authors is a cell line that produces high titer recombinant hepatitis D virus (HDV) and allows the study of viral particles morphogenesis and infectivity, where they observed an increased accumulation of edited version of the viral genomes within secreted HDV viral particles over time that is accompanied with a decrease in viral particle infectivity.
GAPDH overexpression in the T cell lineage promotes angioimmunoblastic T cell lymphoma through an NF-κB-dependent mechanism
Laura Mondragón,Rana Mhaidly,Gian Marco De Donatis,Marie Tosolini,Pascal Dao,Anthony Martin,Caroline Pons,Johanna Chiche,Marie Jacquin,Véronique Imbert,Emma Proïcs,Laurent Boyer,Anne Doye,Frederic Luciano,Jaap G Neels,Frédéric Coutant,Nicole Fabien,Laura Sormani,Camila Rubio-Patiño,Jozef P. Bossowski,Florian Muller,Sandrine Marchetti,Elodie Villa,Jean-François Peyron,Philippe Gaulard,François Lemonnier,Vahid Asnafi,Laurent Genestier,Rachid Benhida,Jean-Jacques Fournié,Thierry Passeron,Jean-Ehrland Ricci,Els Verhoeyen,Els Verhoeyen +33 more
TL;DR: A NIK inhibitor is developed to reveal that targeting the NF-κB pathway prolonged AITL-bearing mouse survival alone and in combination with anti-PD-1, suggesting the therapeutic potential of targeting NF- KakB signaling in A ITL.
Insights on the antiviral mechanisms of action of the TLR1/2 agonist Pam3CSK4 in hepatitis B virus (HBV)-infected hepatocytes.
Manon Desmares,Marion Delphin,Brieux Chardès,Caroline Pons,Juliette Riedinger,Maud Michelet,Michel Rivoire,Bernard Verrier,Anna Salvetti,Julie Lucifora,David Durantel +10 more
TL;DR: In this paper , the effect of TLR2 agonist Pam3CSK4 on HBV RNA production and cccDNA levels was investigated in in vitro cultivated human hepatocytes, based on both primary human hepatocyte (PHH) and non-transformed HepaRG cell line.