Caroline L Relton
University of Bristol
442 Papers
923 Citations
Caroline L Relton is an academic researcher from University of Bristol. The author has contributed to research in topics: DNA methylation & Medicine. The author has an hindex of 71, co-authored 394 publications. Previous affiliations of Caroline L Relton include Health Science University & University of Newcastle.
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Papers
Psychosocial adversity and socioeconomic position during childhood and epigenetic age: Analysis of two prospective cohort studies
Rebecca B Lawn,Emma L Anderson,Matthew Suderman,Andrew J Simpkin,Andrew J Simpkin,Tom R. Gaunt,Andrew E. Teschendorff,Andrew E. Teschendorff,Martin Widschwendter,Rebecca Hardy,Diana Kuh,Caroline L Relton,Laura D Howe +12 more
TL;DR: DNA methylation age acceleration is associated with sexual abuse, suggesting a potential mechanism linking sexual abuse with adverse outcomes and Replication studies with larger sample sizes are warranted.
Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns Findings From the Pregnancy and Childhood Epigenetics Consortium
Nabila Kazmi,Gemma C Sharp,Sarah E. Reese,Florianne O.L. Vehmeijer,Jari Lahti,Christian M. Page,Weiming Zhang,Sheryl L. Rifas-Shiman,Faisal I. Rezwan,Andrew J Simpkin,Kimberley Burrows,Tom G. Richardson,Diana L. Santos Ferreira,Abigail Fraser,Quaker E. Harmon,Shanshan Zhao,Vincent W. V. Jaddoe,Darina Czamara,Elisabeth B. Binder,Maria C. Magnus,Siri E. Håberg,Wenche Nystad,Ellen A. Nohr,Anne P. Starling,Katerina Kechris,Ivana V. Yang,Dawn L. DeMeo,Augusto A. Litonjua,Andrea A. Baccarelli,Emily Oken,John W. Holloway,Wilfried Karmaus,Syed Hasan Arshad,Dana Dabelea,Thorkild I. A. Sørensen,Hannele Laivuori,Katri Räikkönen,Janine F. Felix,Stephanie J. London,Marie-France Hivert,Tom R. Gaunt,Debbie A Lawlor,Caroline L Relton +42 more
TL;DR: In this paper, the association between preeclampsia and DNA methylation was found to be associated with low birth weight, shorter gestational age, and increased risk of maternal and offspring cardiovascular diseases later in life.
Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age
Simon Kebede Merid,Alexei Novoloaca,Gemma C Sharp,Leanne K. Küpers,Leanne K. Küpers,Leanne K. Küpers,Alvin T. Kho,Ritu Roy,Lu Gao,Isabella Annesi-Maesano,Pooja Jain,Michelle Plusquin,Michelle Plusquin,Manolis Kogevinas,Catherine Allard,Florianne O L Vehmeijer,Nabila Kazmi,Lucas A. Salas,Faisal I. Rezwan,Hongmei Zhang,Sylvain Sebert,Sylvain Sebert,Darina Czamara,Sheryl L. Rifas-Shiman,Phillip E. Melton,Phillip E. Melton,Debbie A Lawlor,Göran Pershagen,Carrie V. Breton,Karen Huen,Nour Baïz,Luigi Gagliardi,Tim S. Nawrot,Tim S. Nawrot,Eva Corpeleijn,Patrice Perron,Patrice Perron,Liesbeth Duijts,Ellen A. Nohr,Mariona Bustamante,Susan Ewart,Wilfried Karmaus,Shanshan Zhao,Christian M. Page,Zdenko Herceg,Marjo-Riitta Järvelin,Jari Lahti,Jari Lahti,Andrea A. Baccarelli,Denise Anderson,Priyadarshini Kachroo,Caroline L Relton,Anna Bergström,Brenda Eskenazi,Munawar Hussain Soomro,Paolo Vineis,Harold Snieder,Luigi Bouchard,Luigi Bouchard,Vincent W. V. Jaddoe,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Martine Vrijheid,S. Hasan Arshad,John W. Holloway,Siri E. Håberg,Per Magnus,Terence Dwyer,Terence Dwyer,Elisabeth B. Binder,Elisabeth B. Binder,Dawn L. DeMeo,Judith M. Vonk,John P. Newnham,Kelan G. Tantisira,Inger Kull,Inger Kull,Joseph L. Wiemels,Barbara Heude,Jordi Sunyer,Wenche Nystad,Monica Cheng Munthe-Kaas,Monica Cheng Munthe-Kaas,Katri Räikkönen,Emily Oken,Rae-Chi Huang,Scott T. Weiss,Josep M. Antó,Jean Bousquet,Jean Bousquet,Ashok Kumar,Ashok Kumar,Ashok Kumar,Cilla Söderhäll,Catarina Almqvist,Catarina Almqvist,Andres Cardenas,Olena Gruzieva,Cheng-Jian Xu,Sarah E. Reese,Juha Kere,Juha Kere,Petter Brodin,Petter Brodin,Petter Brodin,Olivia Solomon,Matthias Wielscher,Nina Holland,Akram Ghantous,Marie-France Hivert,Marie-France Hivert,Janine F. Felix,Gerard H. Koppelman,Stephanie J. London,Erik Melén,Erik Melén +115 more
TL;DR: In this article, a meta-analysis of Illumina's HumanMethylation450-array associations between gestational age and cord blood DNA methylation in 3648 newborns from 17 cohorts without common pregnancy complications, induced delivery or caesarean section was performed.
Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer
James Yarmolinsky,Caroline J. Bull,Emma E. Vincent,Jamie Robinson,Axel Walther,George Davey Smith,Sarah J Lewis,Caroline L Relton,Richard M. Martin,Richard M. Martin +9 more
TL;DR: To evaluate the association of genetically proxied inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase with epithelial ovarian cancer among the general population and in BRCA1/2 mutation carriers, single-nucleotide polymorphisms associated with low-density lipoprotein cholesterol in a genome-wide association study (GWAS) meta-analysis were used.
DNA methylation as a marker for prenatal smoke exposure in adults.
TL;DR: Robust evidence is provided that maternal smoking in pregnancy is associated with changes in DNA methylation that persist in the exposed offspring for many years after prenatal exposure.