Caroline Eisele
Icahn School of Medicine at Mount Sinai
18 Papers
13 Citations
Caroline Eisele is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 3, co-authored 9 publications.
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Papers
Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice.
Joana Torres,Jianzhong Hu,Akihiro Seki,Caroline Eisele,Nilendra Nair,Ruiqi Huang,Leonid Tarassishin,Bindia Jharap,Justin Côté-Daigneault,Qixing Mao,Ilaria Mogno,Graham J. Britton,Mathieu Uzzan,Ching-Lynn Chen,Asher Kornbluth,James F. George,Peter Legnani,Elana Maser,Holly Loudon,Joanne Stone,Marla Dubinsky,Jeremiah J. Faith,Jose C. Clemente,Saurabh Mehandru,Jean-Frederic Colombel,Inga Peter +25 more
TL;DR: Aberrant gut microbiota composition persists during pregnancy with IBD and alters the bacterial diversity and abundance in the infant stool.
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Longitudinal Changes in Fecal Calprotectin Levels Among Pregnant Women With and Without Inflammatory Bowel Disease and Their Babies.
Eun Soo Kim,Leonid Tarassishin,Caroline Eisele,Amélie Barré,Nilendra Nair,Alexa Rendon,Kelly Hawkins,Anketse Debebe,Sierra R. White,Anne Thjømøe,Einar Mørk,Mario Bento-Miranda,Hinaben J. Panchal,Manasi Agrawal,Anish Patel,Ching-Lynn Chen,Asher Kornbluth,James F. George,Peter Legnani,Elana Maser,Holly Loudon,Maria-Teresa Mella,Joanne Stone,Marla Dubinsky,João Sabino,Joana Torres,Jean-Frederic Colombel,Inga Peter,Jianzhong Hu +28 more
TL;DR: Pregnancy is associated with decreased inflammatory activity in mothers with IBD and higher FC levels in babies born to IBD mothers suggest subclinical inflammation in early life whose long-term consequences are uncertain.
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Breastfeeding Is Associated with Lower Likelihood of Helicobacter Pylori Colonization in Babies, Based on a Prospective USA Maternal-Infant Cohort
Leonid Tarassishin,Caroline Eisele,Alexa Rendon,Anketse Debebe,Kelly Hawkins,Christen M Hillenbrand,Manasi Agrawal,Joana Torres,Richard M. Peek,Joanne Stone,Marla Dubinsky,Jean-Frederic Colombel,Inga Peter,Jianzhong Hu +13 more
TL;DR: Dominant breastfeeding may protect against early H. pylori colonization among babies, and downregulation of pro-inflammatory cytokines such as MMP-10 may be relevant in mediating this protection among breastfed babies, but more data are needed.
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Infants Born to Mothers with Inflammatory Bowel Disease Exhibit Distinct Microbiome Features that Persist Up to 3 Months of Life
Jianzhong Hu,Joana Torres,Caroline Eisele,Nilendra Nair,Hinaben J. Panchal,Xiuliang Bao,Xiaohong Niu,Justin Côté-Daigneault,Bindia Jharap,Elana Maser,Asher Kornbluth,Peter Legnani,James F. George,Marla Dubinsky,Joanne Stone,Ching-Lynn Chen,Jose C. Clemente,Jean-Frederic Colombel,Inga Peter +18 more
TL;DR: Pregnant women with IBD present an enrichment in bacteria from the Gammaproteobacteria class, and a decrease inacteria from the Bacteroidetes phylum, as compared to women without IBD, according to placenta samples.
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