Carlos E. Alvarez
Icahn School of Medicine at Mount Sinai
10 Papers
19 Citations
Carlos E. Alvarez is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Hepatic stellate cell & Hepatic fibrosis. The author has an hindex of 9, co-authored 10 publications.
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Papers
BASIC-LIVER, PANCREAS, AND BILIARY TRACT Immune Stimulation of Hepatic Fibrogenesis by CD8 Cells and Attenuation by Transgenic Interleukin-10 From Hepatocytes
Rifaat Safadi,Masayuki Ohta,Carlos E. Alvarez,M. Isabel Fiel,Meena B. Bansal,Wajahat Z. Mehal,Scott L. Friedman +6 more
- 01 Jan 2004
TL;DR: Transgenic expression of ril-10 in liver leads to reduced fibrosis and alterations in liver lymphocyte subsets both in untreated liver and following fibrosis induction, suggesting that rIL-10's antifibrotic effect was lymphocyte mediated.
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Loss of Matrix Metalloproteinase-2 Amplifies Murine Toxin-Induced Liver Fibrosis by Upregulating Collagen I Expression
Brian Radbill,Ritu Gupta,Maria Celeste M. Ramirez,Analisa DiFeo,John A. Martignetti,Carlos E. Alvarez,Scott L. Friedman,Goutham Narla,Raluca Vrabie,Robert N. Bowles,Yedidya Saiman,Meena B. Bansal +11 more
TL;DR: It is suggested that increased MMP-2 during the progression of liver fibrosis may be an important mechanism for inhibiting type I collagen synthesis by activated HSCs, thereby providing a protective rather than pathologic role.
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Immunomodulatory effects of plasminogen activators on hepatic fibrogenesis
A. A. Higazi,M. El-Haj,Alaa Melhem,Amjad Horani,Orit Pappo,Carlos E. Alvarez,Nidal Muhanna,Scott L. Friedman,Rifaat Safadi +8 more
TL;DR: It is postulate that plasminogen activators affect fibrosis in part by liver‐specific activation of CD8 subsets that govern the fibrogenic activity of hepatic stellate cells.
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Enhanced oral tolerance in transgenic mice with hepatocyte secretion of IL-10.
Rifaat Safadi,Carlos E. Alvarez,Masayuki Ohta,Jens Brimnes,Thomas Kraus,Wajahat Z. Mehal,Jonathan S. Bromberg,Lloyd Mayer,Scott L. Friedman +8 more
TL;DR: IL-10, when transgenically expressed in the liver enhances mucosal tolerance to an oral Ag and has only a modest effect on tolerance in transgenic transgenic mice with sustained hepatocyte-specific expression of rat IL-10.
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with Hepatocyte Secretion of IL-10 Enhanced Oral Tolerance in Transgenic Mice
Lloyd Mayer,Scott L. Friedman Brimnes,Thomas Kraus,Wajahat Z. Mehal,Carlos E. Alvarez,Masayuki Ohta +5 more
- 01 Jan 2013
TL;DR: This article cites 50 articles, 22 of which you can access for free at: Subscriptions, at www.jimmunol.org/content/175/6/3577.full#ref-list-1.
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