Carlos Arocena
Autonomous University of Madrid
8 Papers
209 Citations
Carlos Arocena is an academic researcher from Autonomous University of Madrid. The author has contributed to research in topics: Hepatitis C virus & Cirrhosis. The author has an hindex of 8, co-authored 8 publications.
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Papers
In Vitro Infection of Human Peripheral Blood Mononuclear Cells by GB Virus C/Hepatitis G Virus
Marta Fogeda,Sonia Navas,Julio Martín,Mercedes Casqueiro,Elena Rodríguez,Carlos Arocena,Vicente Carreño +6 more
TL;DR: This study has demonstrated, for the first time, GBV-C replication in human lymphoid cells under experimental in vitro infection conditions.
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Histological Damage in Chronic Hepatitis C Is Not Related to the Extent of Infection in the Liver
Elena Rodríguez-Iñigo,Javier Bartolomé,Susana de Lucas,Félix Manzarbeitia,Margarita Pardo,Carlos Arocena,Jaime Gosálvez,Horacio Oliva,Vicente Carreño +8 more
TL;DR: It is shown that the HCV viremia reflects the extent of the infection in the liver and that the liver injury in chronic HCV infection is not directly related to either the number of infected hepatocytes or the serum HCV RNA concentration.
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Existence of Distinct GB Virus C/Hepatitis G Virus Variants with Different Tropism
Marta Fogeda,Juan Manuel López-Alcorocho,Javier Bartolomé,Carlos Arocena,Maria Angeles Martín,Vicente Carreño +5 more
TL;DR: The results support the existence of different GBV-C/HGV variants with different tissue tropism, and show that all PBMC sequences grouped together into a branch which was separate from those of the inoculum.
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Effects of delayed freezing of liver biopsies on the detection of hepatitis C virus RNA strands.
TL;DR: Freezing of liver samples immediately after extraction is crucial to avoid false negative HCV-RNA detection results, especially for the antigenomic RNA strand.
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Randomized controlled trial of recombinant human granulocyte-macrophage colony-stimulating factor for the treatment of chronic hepatitis c.
Vicente Carreño,Julio Martín,Margarita Pardo,Alvaro Brotons,Pedro Anchı́a,Sonia Navas,M N Fernández,Carlos Arocena,Juan Antonio Quiroga +8 more
TL;DR: Granulocyte-macrophage colony-stimulating factor administration is safe and shows effects against HCV; the GM-CSF/IFNalpha2b combination has an additional-but transient-antiviral activity in chronic hepatitis C.
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