Camilla Lund
University of Copenhagen
8 Papers
3 Citations
Camilla Lund is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Acid-sensing ion channel & Chemistry. The author has an hindex of 4, co-authored 5 publications.
Chat about Author
Papers
Mechanism and site of action of big dynorphin on ASIC1a.
Christian B. Borg,Nina Braun,Stephanie A. Heusser,Yasmin Bay,Daniel Weis,Iacopo Galleano,Camilla Lund,Weihua Tian,Linda M. Haugaard-Kedström,Eric P. Bennett,Timothy Lynagh,Kristian Strømgaard,Jacob Andersen,Stephan A. Pless +13 more
TL;DR: The mechanism of how BigDyn modulates ASIC1a is defined, the acidic pocket is identified as the binding site forBigDyn, and this cavity is highlighted as an important site for the development of ASIC-targeting therapeutics.
43
The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions
Jens Lund,Alberte Wollesen Breum,C. Gil,Sarah Falk,Frederike Sass,Marie S. Isidor,Oksana Dmytriyeva,Pablo Ranea-Robles,C. V. Mathiesen,Astrid L. Basse,O. S. Johansen,Nicole Fadahunsi,Camilla Lund,Trine S. Nicolaisen,Anders B. Klein,Brice Emanuelli,Maximilian Kleinert,Charlotte Mehlin Sorensen,Zachary Gerhart-Hines,Christoffer Clemmensen +19 more
TL;DR: It is shown that the hypertonicity of the injected solutions can drive the metabolic effects attributed to pharmacological administration of lactate, and the importance of taking treatment osmolarity and counterions into account in the experimental design is highlighted.
27
Muscarinic receptors in energy homeostasis: Physiology and pharmacology.
TL;DR: This MiniReview scrutinizes the literature that has formed the knowledge of muscarinic acetylcholine receptors (mAChRs) in energy homeostasis and discusses the therapeutic prospects of targeting mAChRs for the treatment of obesity and type 2 diabetes.
12
Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
Camilla Lund,Pablo Ranea-Robles,Sarah Falk,Dylan M Rausch,Grethe Skovbjerg,Victoria Kamma Vibe-Petersen,Nathalie Krauth,Jacob Lercke Skytte,Vasiliki Vana,Urmas Roostalu,Tune H. Pers,Jens Lund,Christoffer Clemmensen +12 more
TL;DR: It is demonstrated that the defense against overfeeding-induced weight gain remains intact in obesity and involves mechanisms independent of both FGF21 and MC4R, and that FGF21 is dispensable for this defense against weight gain.
6
Mechanism and site of action of big dynorphin on ASIC1a
Christian B. Borg,Nina Braun,Stephanie A. Heusser,Yasmin Bay,Daniel Weis,Iacopo Galleano,Camilla Lund,Weihua Tian,Linda M. Haugaard-Kedström,Eric P. Bennett,Timothy Lynagh,Kristian Strømgaard,Jacob Andersen,Stephan A. Pless +13 more
TL;DR: Overall, the data define the mechanism of how BigDyn modulates ASIC1a, identify the acidic pocket as the binding site forBigDyn and thus highlight this cavity as an important site for the development of ASIC-targeting therapeutics.
4