Caleb J. Bashor
University of California, San Francisco
6 Papers
8 Citations
Caleb J. Bashor is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Synthetic biology & Ste5. The author has an hindex of 6, co-authored 6 publications.
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Papers
The Ste5 Scaffold Allosterically Modulates Signaling Output of the Yeast Mating Pathway
Roby P. Bhattacharyya,Attila Reményi,Matthew C. Good,Caleb J. Bashor,Arnold M. Falick,Wendell A. Lim +5 more
TL;DR: It is found that the Ste5 scaffold has a more active role in the yeast mating pathway: A fragment of Ste5 allosterically activated autophosphorylation of the mitogen-activated protein kinase Fus3 appears to have a negative regulatory role.
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Rewiring Cells: Synthetic biology as a tool to interrogate the organizational principles of living systems
TL;DR: Recent work that uses synthetic biology approaches to investigate the organization and function of cellular networks are outlined, and a vision for a synthetic biology toolkit that could be used to interrogate the design principles of diverse systems is described.
SYNZIP Protein Interaction Toolbox: in Vitro and in Vivo Specifications of Heterospecific Coiled-Coil Interaction Domains
Kenneth Evan Thompson,Caleb J. Bashor,Wendell A. Lim,Amy E. Keating +3 more
- 01 Feb 2012
TL;DR: In this paper, the authors report characterization of 22 previously published heterospecific synthetic coiled-coil peptides called SYNZIPs, which can be used to control protein association.
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SYNZIP protein interaction toolbox: in vitro and in vivo specifications of heterospecific coiled-coil interaction domains.
TL;DR: Characterization of 22 previously published heterospecific synthetic coiled-coil peptides called SYNZIPs dramatically increases the number of available protein interaction parts for synthetic biology and should facilitate a wide range of molecular engineering applications.
Engineering dynamical control of cell fate switching using synthetic phospho-regulons
Russell M. Gordley,Russell M. Gordley,Reid E. Williams,Caleb J. Bashor,Jared E. Toettcher,Shude Yan,Wendell A. Lim,Wendell A. Lim +7 more
TL;DR: The development of a modular approach for flexibly engineering phosphorylation circuits using designed phospho-regulon motifs is reported, which open up the possibility to engineer cells with customized dynamical control.